DLX1008 (brolucizumab), a single-chain anti-VEGF-A antibody fragment with low picomolar affinity, leads to tumor involution in an in vivo model of Kaposi Sarcoma

• Anthony B. Eason,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, United States of America, Department of Microbiology and Immunology, The University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, United States of America

  http://orcid.org/0000-0002-6723-7999

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• Sang-Hoon Sin,

  Roles Conceptualization, Data curation, Methodology, Project administration, Validation, Writing – review & editing

  Affiliations Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, United States of America, Department of Microbiology and Immunology, The University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, United States of America

  http://orcid.org/0000-0002-6503-4960

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• Mohsin Shah,

  Roles Investigation, Methodology, Validation

  Affiliations Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, United States of America, Department of Microbiology and Immunology, The University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, United States of America

  http://orcid.org/0000-0002-1491-356X

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• Hong Yuan,

  Roles Conceptualization, Resources, Writing – review & editing

  Affiliation Biomedical Research Imaging Center, The University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, United States of America

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• Douglas J. Phillips,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Writing – review & editing

  Affiliation Cell Medica, Zurich, Switzerland

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• Miriam Droste,

  Roles Formal analysis, Investigation, Validation, Writing – review & editing

  Affiliation Cell Medica, Zurich, Switzerland

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• Abdijapar Shamshiev,

  Roles Formal analysis, Investigation, Validation, Writing – review & editing

  Affiliation Cell Medica, Zurich, Switzerland

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• Dirk P. Dittmer

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Resources, Supervision, Writing – review & editing

  * E-mail: ddittmer@med.unc.edu

  Affiliations Lineberger Comprehensive Cancer Center, The University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, United States of America, Department of Microbiology and Immunology, The University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina, United States of America

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