Odiparcil, a potential glycosaminoglycans clearance therapy in mucopolysaccharidosis VI—Evidence from in vitro and in vivo models

Eugeni Entchev; Ingrid Jantzen; Philippe Masson; Stephanie Bocart; Bruno Bournique; Jean-Michel Luccarini; Andre Bouchot; Olivier Lacombe; Jean-Louis Junien; Pierre Broqua; Mireille Tallandier

doi:10.1371/journal.pone.0233032

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Open Access

Peer-reviewed

Research Article

Odiparcil, a potential glycosaminoglycans clearance therapy in mucopolysaccharidosis VI—Evidence from in vitro and in vivo models

Eugeni Entchev ,

Roles Conceptualization, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing

* E-mail: eugeni.entchev@inventivapharma.com (EE); mireille.tallandier@inventivapharma.com (MT)

Affiliation Inventiva Pharma, Bourgogne-Franche-Comté, Daix, France

http://orcid.org/0000-0003-0744-5929

⨯
Ingrid Jantzen,

Roles Investigation, Methodology

Affiliation Inventiva Pharma, Bourgogne-Franche-Comté, Daix, France

http://orcid.org/0000-0001-6057-0724

⨯
Philippe Masson,

Roles Conceptualization, Investigation, Methodology, Supervision

Affiliation Inventiva Pharma, Bourgogne-Franche-Comté, Daix, France
⨯
Stephanie Bocart,

Roles Investigation, Methodology

Affiliation Inventiva Pharma, Bourgogne-Franche-Comté, Daix, France
⨯
Bruno Bournique,

Roles Investigation, Methodology

Affiliation Inventiva Pharma, Bourgogne-Franche-Comté, Daix, France
⨯
Jean-Michel Luccarini,

Roles Methodology, Project administration, Supervision

Affiliation Inventiva Pharma, Bourgogne-Franche-Comté, Daix, France
⨯
Andre Bouchot,

Roles Investigation, Methodology

Affiliation DImaCell Core Facility, Inserm UMR1231 CellImaP site, Université de Bourgogne, Bourgogne-Franche-Comté, Dijon, France
⨯
Olivier Lacombe,

Roles Methodology, Supervision

Affiliation Inventiva Pharma, Bourgogne-Franche-Comté, Daix, France
⨯
Jean-Louis Junien,

Roles Conceptualization, Supervision, Writing – review & editing

Affiliation Inventiva Pharma, Bourgogne-Franche-Comté, Daix, France
⨯
Pierre Broqua,

Roles Conceptualization, Supervision, Writing – review & editing

Affiliation Inventiva Pharma, Bourgogne-Franche-Comté, Daix, France
⨯
Mireille Tallandier

Roles Conceptualization, Project administration, Supervision, Writing – review & editing

* E-mail: eugeni.entchev@inventivapharma.com (EE); mireille.tallandier@inventivapharma.com (MT)

Affiliation Inventiva Pharma, Bourgogne-Franche-Comté, Daix, France
⨯

Odiparcil, a potential glycosaminoglycans clearance therapy in mucopolysaccharidosis VI—Evidence from in vitro and in vivo models

Eugeni Entchev,
Ingrid Jantzen,
Philippe Masson,
Stephanie Bocart,
Bruno Bournique,
Jean-Michel Luccarini,
Andre Bouchot,
Olivier Lacombe,
Jean-Louis Junien,
Pierre Broqua

Published: May 15, 2020
https://doi.org/10.1371/journal.pone.0233032

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