Pooling individual participant data from randomized controlled trials: Exploring potential loss of information

• Lennard L. van Wanrooij ,

  Roles Conceptualization, Formal analysis, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: l.l.vanwanrooij@amc.uva.nl

  Affiliation Department of Neurology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands

  http://orcid.org/0000-0002-1349-8261

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• Marieke P. Hoevenaar-Blom,

  Roles Conceptualization, Data curation, Methodology, Supervision, Writing – review & editing

  Affiliations Department of Neurology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands, Department of Neurology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands

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• Nicola Coley,

  Roles Data curation, Writing – review & editing

  Affiliations Department of Epidemiology and Public Health, Toulouse University Hospital, Toulouse, France, INSERM, University of Toulouse UMR1027, Toulouse, France

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• Tiia Ngandu,

  Roles Data curation, Writing – review & editing

  Affiliation Chronic Disease Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland

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• Yannick Meiller,

  Roles Conceptualization, Data curation, Methodology, Writing – review & editing

  Affiliation Department of Information and Operations Management, ESCP Europe, Paris, France

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• Juliette Guillemont,

  Roles Data curation, Writing – review & editing

  Affiliation INSERM, University of Toulouse, Toulouse, France

  http://orcid.org/0000-0002-8608-6751

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• Anna Rosenberg,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Neurology, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland

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• Cathrien R. L. Beishuizen,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Neurology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands

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• Eric P. Moll van Charante,

  Roles Data curation, Writing – review & editing

  Affiliation Department of General Practice, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands

  http://orcid.org/0000-0002-1489-5218

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• Hilkka Soininen,

  Roles Data curation, Writing – review & editing

  Affiliations Department of Neurology, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland, Neurocenter, Neurology, Kuopio University Hospital, Kuopio, Finland

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• Carol Brayne,

  Roles Conceptualization, Data curation, Methodology, Writing – review & editing

  Affiliation Department of Public Health and Primary Care, Cambridge Institute of Public Health, University of Cambridge, Cambridge, United Kingdom

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• Sandrine Andrieu,

  Roles Data curation, Writing – review & editing

  Affiliations Department of Epidemiology and Public Health, Toulouse University Hospital, Toulouse, France, INSERM, University of Toulouse UMR1027, Toulouse, France

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• Miia Kivipelto,

  Roles Data curation, Writing – review & editing

  Affiliations Chronic Disease Prevention Unit, National Institute for Health and Welfare, Helsinki, Finland, Department of Neurology, Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland, Aging Research Center, Karolinska Institutet, Stockholm University, Stockholm, Sweden, Karolinska Institutet Center for Alzheimer Research, Stockholm, Sweden

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• Edo Richard

  Roles Conceptualization, Data curation, Funding acquisition, Methodology, Supervision, Writing – review & editing

  Affiliations Department of Neurology, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands, Department of Neurology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands

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