Substantial improvement of tetraene macrolide production in Streptomyces diastatochromogenes by cumulative drug resistance mutations

• Jing-Xuan Fan,

  Roles Writing – original draft

  Affiliation Zhejiang Provincial Key Laboratory of Biometrology and Inspection & Quarantine, College of Life Sciences, China Jiliang University, Hangzhou, China

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• Yang Song,

  Roles Formal analysis

  Affiliation Zhejiang Provincial Key Laboratory of Biometrology and Inspection & Quarantine, College of Life Sciences, China Jiliang University, Hangzhou, China

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• Gu Tang,

  Roles Investigation

  Affiliation Zhejiang Provincial Key Laboratory of Biometrology and Inspection & Quarantine, College of Life Sciences, China Jiliang University, Hangzhou, China

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• Kozo Ochi,

  Roles Writing – review & editing

  Affiliation Department of Life Science, Hiroshima Institute of Technology, Hiroshima, Japan

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• Xu-Ping Shentu ,

  Roles Data curation, Writing – original draft, Writing – review & editing

  * E-mail: stxp@cjlu.edu.cn (XPS); yxp@cjlu.edu.cn (XPY)

  Affiliation Zhejiang Provincial Key Laboratory of Biometrology and Inspection & Quarantine, College of Life Sciences, China Jiliang University, Hangzhou, China

  http://orcid.org/0000-0003-4524-0334

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• Xiao-Ping Yu

  Roles Visualization

  * E-mail: stxp@cjlu.edu.cn (XPS); yxp@cjlu.edu.cn (XPY)

  Affiliation Zhejiang Provincial Key Laboratory of Biometrology and Inspection & Quarantine, College of Life Sciences, China Jiliang University, Hangzhou, China

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