Gastrointestinal absorption of pimozide is enhanced by inhibition of P-glycoprotein

• Hiroki Morishita ,

  Contributed equally to this work with: Hiroki Morishita, Kozue Okawa, Kentaro Yano

  Roles Investigation, Methodology, Project administration, Writing – original draft

  Affiliations Laboratory of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Takasaki University of Health and Welfare, Nakaorui-machi, Takasaki, Gunma, Japan, Department of Pharmacy, Saiseikai Maebashi Hospital, Kamishinden-machi, Maebashi, Gunma, Japan

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• Kozue Okawa ,

  Contributed equally to this work with: Hiroki Morishita, Kozue Okawa, Kentaro Yano

  Roles Investigation, Methodology

  Affiliation Laboratory of Biopharmaceutics, Faculty of Pharmacy, Takasaki University of Health and Welfare, Nakaorui-machi, Takasaki, Gunma, Japan

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• Misaki Ishii ,

  Roles Investigation, Methodology

  ¶‡ These authors also contributed equally to this work.

  Affiliation Laboratory of Biopharmaceutics, Faculty of Pharmacy, Takasaki University of Health and Welfare, Nakaorui-machi, Takasaki, Gunma, Japan

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• Kenta Mizoi,

  Roles Investigation

  Affiliation Laboratory of Biopharmaceutics, Faculty of Pharmacy, Takasaki University of Health and Welfare, Nakaorui-machi, Takasaki, Gunma, Japan

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• Masa-aki Ito,

  Roles Writing – review & editing

  Affiliation Laboratory of Pharmacology, Faculty of Pharmacy, Takasaki University of Health and Welfare, Nakaorui-machi, Takasaki, Gunma, Japan

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• Hiroshi Arakawa ,

  Roles Investigation

  ¶‡ These authors also contributed equally to this work.

  Affiliation Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kakuma-machi, Kanazawa, Japan

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• Kentaro Yano ,

  Contributed equally to this work with: Hiroki Morishita, Kozue Okawa, Kentaro Yano

  Roles Investigation, Project administration

  Current address: Laboratory of Drug Metabolism and Pharmacokinetics, Yokohama University of Pharmacy, Matano-cho, Totsuka-ku, Yokohama, Kanagawa, Japan

  Affiliation Laboratory of Biopharmaceutics, Faculty of Pharmacy, Takasaki University of Health and Welfare, Nakaorui-machi, Takasaki, Gunma, Japan

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• Takuo Ogihara

  Roles Supervision, Writing – review & editing

  * E-mail: togihara@takasaki-u.ac.jp

  Affiliations Laboratory of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Takasaki University of Health and Welfare, Nakaorui-machi, Takasaki, Gunma, Japan, Laboratory of Biopharmaceutics, Faculty of Pharmacy, Takasaki University of Health and Welfare, Nakaorui-machi, Takasaki, Gunma, Japan

  https://orcid.org/0000-0001-5197-038X

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