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Open Access
Peer-reviewed
Research Article
Both male and female obese ZSF1 rats develop cardiac dysfunction in obesity-induced heart failure with preserved ejection fraction
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Isabel T. N. Nguyen,
Roles Formal analysis, Investigation, Project administration, Validation, Visualization, Writing – original draft, Writing – review & editing
Affiliation Department of Nephrology and Hypertension, University Medical Center Utrecht, Utrecht, The Netherlands
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Maarten M. Brandt ,
Contributed equally to this work with: Maarten M. Brandt, Jens van de Wouw
Roles Formal analysis, Investigation, Writing – review & editing
Affiliation Division of Experimental Cardiology, Department of Cardiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
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Jens van de Wouw ,
Contributed equally to this work with: Maarten M. Brandt, Jens van de Wouw
Roles Formal analysis, Investigation, Writing – review & editing
Affiliation Division of Experimental Cardiology, Department of Cardiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
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Ruben W. A. van Drie,
Roles Formal analysis, Investigation, Writing – review & editing
Affiliation Division of Experimental Cardiology, Department of Cardiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
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Marian Wesseling,
Roles Formal analysis, Investigation, Writing – review & editing
Affiliation Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands
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Maarten J. Cramer,
Roles Supervision, Writing – review & editing
Affiliation Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands
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Saskia C. A. de Jager,
Roles Supervision, Writing – review & editing
Affiliation Laboratory of Experimental Cardiology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands
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Daphne Merkus,
Roles Funding acquisition, Supervision, Writing – review & editing
Affiliations Division of Experimental Cardiology, Department of Cardiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands, Walter Brendel Center of Experimental Medicine (WBex), Munich, Germany, German Center for Cardiovascular Research (DZHK), Partner Site Munich, Munich Heart Alliance (MHA), Munich, Germany
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Dirk J. Duncker,
Roles Funding acquisition, Supervision, Writing – review & editing
Affiliation Division of Experimental Cardiology, Department of Cardiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
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Caroline Cheng,
Roles Funding acquisition, Supervision, Writing – review & editing
Affiliations Department of Nephrology and Hypertension, University Medical Center Utrecht, Utrecht, The Netherlands, Division of Experimental Cardiology, Department of Cardiology, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
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Jaap. A. Joles,
Roles Supervision, Validation, Writing – original draft, Writing – review & editing
Affiliation Department of Nephrology and Hypertension, University Medical Center Utrecht, Utrecht, The Netherlands
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Marianne C. Verhaar
Roles Funding acquisition, Supervision, Validation, Writing – review & editing
* E-mail: M.C.Verhaar@umcutrecht.nl
Affiliation Department of Nephrology and Hypertension, University Medical Center Utrecht, Utrecht, The Netherlands
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Both male and female obese ZSF1 rats develop cardiac dysfunction in obesity-induced heart failure with preserved ejection fraction
- Isabel T. N. Nguyen,
- Maarten M. Brandt,
- Jens van de Wouw,
- Ruben W. A. van Drie,
- Marian Wesseling,
- Maarten J. Cramer,
- Saskia C. A. de Jager,
- Daphne Merkus,
- Dirk J. Duncker,
- Caroline Cheng
- Published: May 6, 2020
- https://doi.org/10.1371/journal.pone.0232399