Tumor-associated autoantibodies in combination with alpha-fetoprotein for detection of early stage hepatocellular carcinoma

Christopher Welberry; Isabel Macdonald; Jane McElveen; Celine Parsy-Kowalska; Jared Allen; Graham Healey; William Irving; Andrea Murray; Caroline Chapman

doi:10.1371/journal.pone.0232247

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Open Access

Peer-reviewed

Research Article

Tumor-associated autoantibodies in combination with alpha-fetoprotein for detection of early stage hepatocellular carcinoma

Christopher Welberry ,

* E-mail: cwelberry@googlemail.com, chris.welberry@oncimmune.co.uk

Affiliations Oncimmune ltd, Nottingham, United Kingdom, School of Medicine, University of Nottingham, Nottingham, United Kingdom
⨯
Isabel Macdonald,

Roles Conceptualization, Writing – original draft, Writing – review & editing

Affiliation Oncimmune ltd, Nottingham, United Kingdom

http://orcid.org/0000-0002-0178-4463

⨯
Jane McElveen,

Roles Conceptualization, Investigation, Writing – original draft, Writing – review & editing

Affiliation Oncimmune ltd, Nottingham, United Kingdom
⨯
Celine Parsy-Kowalska,

Roles Conceptualization, Writing – original draft, Writing – review & editing

Affiliation Oncimmune ltd, Nottingham, United Kingdom
⨯
Jared Allen,

Roles Conceptualization, Data curation, Formal analysis, Writing – original draft, Writing – review & editing

Affiliations Oncimmune ltd, Nottingham, United Kingdom, School of Medicine, University of Nottingham, Nottingham, United Kingdom
⨯
Graham Healey,

Roles Conceptualization, Formal analysis, Writing – original draft, Writing – review & editing

Affiliation Oncimmune ltd, Nottingham, United Kingdom
⨯
William Irving,

Roles Conceptualization, Resources, Writing – original draft, Writing – review & editing

Affiliation NIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and the University of Nottingham, Nottingham, United Kingdom
⨯
Andrea Murray,

Roles Conceptualization, Resources, Writing – original draft, Writing – review & editing

Affiliation Oncimmune ltd, Nottingham, United Kingdom
⨯
Caroline Chapman

Roles Conceptualization, Resources, Writing – original draft, Writing – review & editing

Affiliations School of Medicine, University of Nottingham, Nottingham, United Kingdom, Bowel Cancer Screening Program, Nottingham University NHS Trust, Nottingham, United Kingdom
⨯

Tumor-associated autoantibodies in combination with alpha-fetoprotein for detection of early stage hepatocellular carcinoma

Christopher Welberry,
Isabel Macdonald,
Jane McElveen,
Celine Parsy-Kowalska,
Jared Allen,
Graham Healey,
William Irving,
Andrea Murray,
Caroline Chapman

Published: May 6, 2020
https://doi.org/10.1371/journal.pone.0232247

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Hepatocellular carcinoma
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Biomarkers
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Liver diseases
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Autoantibodies
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Enzyme-linked immunoassays
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Lung and intrathoracic tumors
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Cancers and neoplasms
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Non-small cell lung cancer
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