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Open Access
Peer-reviewed
Research Article
Novel malaria antigen Plasmodium yoelii E140 induces antibody-mediated sterile protection in mice against malaria challenge
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Emily C. Smith ,
Contributed equally to this work with: Emily C. Smith, Keith J. Limbach
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing
Affiliations Malaria Department, Naval Medical Research Center, Silver Spring, Maryland, United States of America, Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (HJF), Bethesda, Maryland, United States of America
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Keith J. Limbach ,
Contributed equally to this work with: Emily C. Smith, Keith J. Limbach
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Resources, Supervision, Writing – original draft, Writing – review & editing
Affiliations Malaria Department, Naval Medical Research Center, Silver Spring, Maryland, United States of America, Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (HJF), Bethesda, Maryland, United States of America
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Nonenipha Rangel,
Roles Data curation, Investigation, Methodology, Writing – review & editing
Affiliations Malaria Department, Naval Medical Research Center, Silver Spring, Maryland, United States of America, CAMRIS International, Bethesda, Maryland, United States of America
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Kyosuke Oda,
Roles Data curation, Investigation, Methodology, Writing – review & editing
Affiliations Malaria Department, Naval Medical Research Center, Silver Spring, Maryland, United States of America, CAMRIS International, Bethesda, Maryland, United States of America
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Jessica S. Bolton,
Roles Investigation, Methodology, Writing – review & editing
Affiliations Malaria Department, Naval Medical Research Center, Silver Spring, Maryland, United States of America, Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (HJF), Bethesda, Maryland, United States of America
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Mengyan Du,
Roles Investigation, Writing – review & editing
Current address: Meso Scale Diagnostics, Rockville, Maryland, United States of America
Affiliations Malaria Department, Naval Medical Research Center, Silver Spring, Maryland, United States of America, Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (HJF), Bethesda, Maryland, United States of America
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Kalpana Gowda,
Roles Investigation, Writing – review & editing
Affiliation Malaria Department, Naval Medical Research Center, Silver Spring, Maryland, United States of America
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Jianyang Wang,
Roles Investigation, Writing – review & editing
Current address: Uniformed Services University of the Health Sciences, Bethesda, Maryland, United States of America
Affiliations Malaria Department, Naval Medical Research Center, Silver Spring, Maryland, United States of America, CAMRIS International, Bethesda, Maryland, United States of America
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J. Kathleen Moch,
Roles Investigation, Writing – review & editing
Current address: Malaria Biologics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America; General Dynamics Information Technology, Inc., Frederick, Maryland, United States of America
Affiliations Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (HJF), Bethesda, Maryland, United States of America, Malaria Biologics Branch, Walter Reed Army Institute of Research, Silver Spring, Maryland, United States of America
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Sharvari Sonawane,
Roles Investigation, Writing – review & editing
Current address: Department of Pediatrics Allergy and Immunology, University of Rochester School of Medicine and Dentistry, Rochester, New York, United States of America
Affiliations Malaria Department, Naval Medical Research Center, Silver Spring, Maryland, United States of America, Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (HJF), Bethesda, Maryland, United States of America
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Rachel Velasco,
Roles Investigation, Writing – review & editing
Current address: Malaria Department, Naval Medical Research Center, Silver Spring, Maryland, United States of America; General Dynamics Information Technology, Inc., Frederick, Maryland, United States of America
Affiliations Malaria Department, Naval Medical Research Center, Silver Spring, Maryland, United States of America, Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (HJF), Bethesda, Maryland, United States of America
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Arnel Belmonte,
Roles Investigation, Writing – review & editing
Current address: Malaria Department, Naval Medical Research Center, Silver Spring, Maryland, United States of America; General Dynamics Information Technology, Inc., Frederick, Maryland, United States of America
Affiliations Malaria Department, Naval Medical Research Center, Silver Spring, Maryland, United States of America, Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (HJF), Bethesda, Maryland, United States of America
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Rebecca Danner,
Roles Investigation, Writing – review & editing
Current address: Medical College of Wisconsin, Milwaukee, Wisconsin, United States of America
Affiliations Malaria Department, Naval Medical Research Center, Silver Spring, Maryland, United States of America, Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (HJF), Bethesda, Maryland, United States of America
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Joanne M. Lumsden,
Roles Project administration, Writing – review & editing
Current address: ERPi Inc., Fairfax, Virginia, United States of America
Affiliations Malaria Department, Naval Medical Research Center, Silver Spring, Maryland, United States of America, Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (HJF), Bethesda, Maryland, United States of America
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Noelle B. Patterson,
Roles Project administration, Writing – review & editing
Affiliations Malaria Department, Naval Medical Research Center, Silver Spring, Maryland, United States of America, Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (HJF), Bethesda, Maryland, United States of America
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Martha Sedegah,
Roles Supervision, Writing – review & editing
Affiliation Malaria Department, Naval Medical Research Center, Silver Spring, Maryland, United States of America
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Michael R. Hollingdale,
Roles Writing – original draft, Writing – review & editing
Affiliations Malaria Department, Naval Medical Research Center, Silver Spring, Maryland, United States of America, Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (HJF), Bethesda, Maryland, United States of America
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Thomas L. Richie,
Roles Supervision, Writing – review & editing
Current address: Sanaria Inc., Rockville, Maryland, United States of America
Affiliation Malaria Department, Naval Medical Research Center, Silver Spring, Maryland, United States of America
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John B. Sacci Jr,
Roles Data curation, Investigation, Writing – review & editing
Affiliation Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
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Eileen D. Villasante,
Roles Supervision, Writing – review & editing
Affiliation Malaria Department, Naval Medical Research Center, Silver Spring, Maryland, United States of America
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Joao C. Aguiar
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Supervision, Writing – original draft, Writing – review & editing
* E-mail: joao.c.aguiar.ctr@mail.mil
Affiliations Malaria Department, Naval Medical Research Center, Silver Spring, Maryland, United States of America, CAMRIS International, Bethesda, Maryland, United States of America
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Novel malaria antigen Plasmodium yoelii E140 induces antibody-mediated sterile protection in mice against malaria challenge
- Emily C. Smith,
- Keith J. Limbach,
- Nonenipha Rangel,
- Kyosuke Oda,
- Jessica S. Bolton,
- Mengyan Du,
- Kalpana Gowda,
- Jianyang Wang,
- J. Kathleen Moch,
- Sharvari Sonawane
- Published: May 14, 2020
- https://doi.org/10.1371/journal.pone.0232234