Effects of combined drug treatments on Plasmodium falciparum: In vitro assays with doxycycline, ivermectin and efflux pump inhibitors

Riccardo Nodari; Yolanda Corbett; Ilaria Varotto-Boccazzi; Daniele Porretta; Donatella Taramelli; Sara Epis; Claudio Bandi

doi:10.1371/journal.pone.0232171

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Peer-reviewed

Research Article

Effects of combined drug treatments on Plasmodium falciparum: In vitro assays with doxycycline, ivermectin and efflux pump inhibitors

Riccardo Nodari,

Roles Conceptualization, Formal analysis, Investigation, Writing – original draft

Affiliations Department of Biosciences and Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, University of Milan, Milan, Italy, Centro Interuniversitario di Ricerca sulla Malaria/Italian Malaria Network, Milan, Italy
⨯
Yolanda Corbett,

Roles Conceptualization, Investigation

Affiliations Department of Biosciences and Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, University of Milan, Milan, Italy, Centro Interuniversitario di Ricerca sulla Malaria/Italian Malaria Network, Milan, Italy
⨯
Ilaria Varotto-Boccazzi,

Roles Data curation, Formal analysis

Affiliations Department of Biosciences and Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, University of Milan, Milan, Italy, Centro Interuniversitario di Ricerca sulla Malaria/Italian Malaria Network, Milan, Italy
⨯
Daniele Porretta,

Roles Data curation, Formal analysis

Affiliation Department of Environmental Biology, Sapienza University of Rome, Rome, Italy
⨯
Donatella Taramelli,

Roles Conceptualization, Funding acquisition, Supervision

Affiliations Centro Interuniversitario di Ricerca sulla Malaria/Italian Malaria Network, Milan, Italy, Department of Pharmacological and Biomolecular Sciences, University of Milan, Milan, Italy
⨯
Sara Epis,

Roles Conceptualization, Funding acquisition, Supervision

Affiliations Department of Biosciences and Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, University of Milan, Milan, Italy, Centro Interuniversitario di Ricerca sulla Malaria/Italian Malaria Network, Milan, Italy

http://orcid.org/0000-0001-8807-4802

⨯
Claudio Bandi

Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

* E-mail: claudio.bandi@unimi.it

Affiliations Department of Biosciences and Pediatric Clinical Research Center Romeo ed Enrica Invernizzi, University of Milan, Milan, Italy, Centro Interuniversitario di Ricerca sulla Malaria/Italian Malaria Network, Milan, Italy
⨯

Effects of combined drug treatments on Plasmodium falciparum: In vitro assays with doxycycline, ivermectin and efflux pump inhibitors

Riccardo Nodari,
Yolanda Corbett,
Ilaria Varotto-Boccazzi,
Daniele Porretta,
Donatella Taramelli,
Sara Epis,
Claudio Bandi

Published: April 23, 2020
https://doi.org/10.1371/journal.pone.0232171

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Doxycycline
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Plasmodium
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Antimalarials
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