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Open Access

Peer-reviewed

Research Article

Adapting Biased Gene Conversion theory to account for intensive GC-content deterioration in the human genome by novel mutations

Rajan Paudel,

Roles Formal analysis, Investigation, Software

Affiliation Program in Bioinformatics and Proteomics/Genomics, University of Toledo, Toledo, OH, United States of America
⨯
Larisa Fedorova,

Roles Conceptualization, Data curation, Validation, Writing – original draft

Affiliation CRI Genetics LLC, Santa Monica, CA, United States of America
⨯
Alexei Fedorov

Roles Conceptualization, Formal analysis, Investigation, Project administration, Visualization, Writing – original draft

* E-mail: Alexei.fedorov@utoledo.edu

Affiliations Program in Bioinformatics and Proteomics/Genomics, University of Toledo, Toledo, OH, United States of America, CRI Genetics LLC, Santa Monica, CA, United States of America, Department of Medicine, University of Toledo, Toledo, OH, United States of America
⨯

Adapting Biased Gene Conversion theory to account for intensive GC-content deterioration in the human genome by novel mutations

Rajan Paudel,
Larisa Fedorova,
Alexei Fedorov

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Published: April 30, 2020
https://doi.org/10.1371/journal.pone.0232167

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Human genomics
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Mutation detection
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Point mutation
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Nucleotides
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Mutation
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Mammalian genomics
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Single nucleotide polymorphisms
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Substitution mutation
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