Identification of differentially expressed genes in actinic keratosis samples treated with ingenol mebutate gel

Sonia Segura; Alejandra Gadea; Lara Nonell; Evelyn Andrades; Silvia Sánchez; Ramon Pujol; Inmaculada Hernández-Muñoz; Agustí Toll

doi:10.1371/journal.pone.0232146

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Open Access

Peer-reviewed

Research Article

Identification of differentially expressed genes in actinic keratosis samples treated with ingenol mebutate gel

Sonia Segura,

Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Resources, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Dermatology, Hospital del Mar, Parc de Salut Mar, Barcelona, Spain
⨯
Alejandra Gadea,

Roles Formal analysis, Investigation, Resources

Affiliations Group of Inflamatory and Neoplasic Dermatological Diseases, IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain, Centre National de la Recherche Scientifique (CNRS), Centre de Recherche Paul Pascal (CRPP), Université de Bordeaux, Pessac, France
⨯
Lara Nonell,

Roles Data curation, Formal analysis, Software

Affiliation MARGenomics, IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain
⨯
Evelyn Andrades,

Roles Investigation, Resources

Affiliation Group of Inflamatory and Neoplasic Dermatological Diseases, IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain
⨯
Silvia Sánchez,

Roles Data curation, Resources

Affiliation Group of Inflamatory and Neoplasic Dermatological Diseases, IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain
⨯
Ramon Pujol,

Roles Funding acquisition, Project administration, Supervision, Writing – review & editing

Affiliation Department of Dermatology, Hospital del Mar, Parc de Salut Mar, Barcelona, Spain
⨯
Inmaculada Hernández-Muñoz,

Roles Conceptualization, Formal analysis, Investigation, Methodology, Resources, Validation, Visualization, Writing – review & editing

Affiliation Group of Inflamatory and Neoplasic Dermatological Diseases, IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain
⨯
Agustí Toll

Roles Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – review & editing

* E-mail: atoll@clinic.cat

Affiliations Department of Dermatology, Hospital Clínic de Barcelona, University of Barcelona, Barcelona, Spain, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain

http://orcid.org/0000-0003-2656-0076

⨯

Identification of differentially expressed genes in actinic keratosis samples treated with ingenol mebutate gel

Sonia Segura,
Alejandra Gadea,
Lara Nonell,
Evelyn Andrades,
Silvia Sánchez,
Ramon Pujol,
Inmaculada Hernández-Muñoz,
Agustí Toll

Published: May 15, 2020
https://doi.org/10.1371/journal.pone.0232146

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Gene expression
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Lesions
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Keratinocytes
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Biopsy
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Gene ontologies
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Microarrays
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Actinic keratosis
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Immune response
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