The novel multi-cytokine inhibitor TO-207 specifically inhibits pro-inflammatory cytokine secretion in monocytes without affecting the killing ability of CAR T cells

• Muneyoshi Futami ,

  Roles Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Writing – original draft

  * E-mail: m-futami@umin.ac.jp

  Affiliation Division of Molecular Therapy, Advanced Clinical Research Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan

  http://orcid.org/0000-0003-1425-6261

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• Keisuke Suzuki,

  Roles Data curation

  Affiliation Research laboratories, Torii Pharmaceutical., Sakura-shi, Japan

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• Satomi Kato,

  Roles Data curation

  Affiliation Division of Molecular Therapy, Advanced Clinical Research Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan

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• Saori Ohmae,

  Roles Data curation

  Affiliation Research laboratories, Torii Pharmaceutical., Sakura-shi, Japan

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• Yoshio Tahara,

  Roles Data curation

  Affiliation Research laboratories, Torii Pharmaceutical., Sakura-shi, Japan

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• Masanori Nojima,

  Roles Formal analysis

  Affiliation Center for Translational Research, The Institute of Medical Science Hospital, The University of Tokyo, Tokyo, Japan

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• Yoichi Imai,

  Roles Supervision

  Affiliation Department of Hematology/Oncology, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan

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• Takayuki Mimura,

  Roles Conceptualization, Methodology, Supervision

  Affiliation Research laboratories, Torii Pharmaceutical., Sakura-shi, Japan

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• Yoshihiro Watanabe,

  Roles Conceptualization, Methodology, Supervision, Writing – review & editing

  Affiliations Research laboratories, Torii Pharmaceutical., Sakura-shi, Japan, Innovative Clinical Research Center, Kanazawa University, Kanazawa, Japan

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• Arinobu Tojo

  Roles Conceptualization, Methodology, Supervision, Writing – review & editing

  Affiliation Division of Molecular Therapy, Advanced Clinical Research Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan

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