Deep learning assessment of breast terminal duct lobular unit involution: Towards automated prediction of breast cancer risk

• Suzanne C. Wetstein ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: s.c.wetstein@tue.nl

  Affiliation Medical Image Analysis Group, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands

  http://orcid.org/0000-0001-8699-5739

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• Allison M. Onken,

  Roles Data curation, Writing – original draft, Writing – review & editing

  Affiliation Department of Pathology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America

  ⨯
• Christina Luffman,

  Roles Data curation, Writing – original draft, Writing – review & editing

  Affiliation Department of Pathology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America

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• Gabrielle M. Baker,

  Roles Conceptualization, Data curation, Writing – original draft, Writing – review & editing

  Affiliation Department of Pathology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America

  ⨯
• Michael E. Pyle,

  Roles Data curation, Writing – original draft, Writing – review & editing

  Affiliation Department of Pathology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America

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• Kevin H. Kensler,

  Roles Data curation, Writing – original draft, Writing – review & editing

  Affiliation Division of Population Sciences, Dana Farber Cancer Institute, Boston, Massachusetts, United States of America

  http://orcid.org/0000-0001-7515-7270

  ⨯
• Ying Liu,

  Roles Data curation, Writing – original draft, Writing – review & editing

  Affiliation Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine and Alvin J. Siteman Cancer Center, St Louis, Missouri, United States of America

  ⨯
• Bart Bakker,

  Roles Methodology, Resources, Writing – original draft, Writing – review & editing

  Affiliation Philips Research Europe, High Tech Campus, Eindhoven, The Netherlands

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• Ruud Vlutters,

  Roles Methodology, Resources, Writing – original draft, Writing – review & editing

  Affiliation Philips Research Europe, High Tech Campus, Eindhoven, The Netherlands

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• Marinus B. van Leeuwen,

  Roles Methodology, Resources, Writing – original draft, Writing – review & editing

  Affiliation Philips Research Europe, High Tech Campus, Eindhoven, The Netherlands

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• Laura C. Collins,

  Roles Conceptualization, Data curation, Writing – original draft, Writing – review & editing

  Affiliation Department of Pathology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America

  ⨯
• Stuart J. Schnitt,

  Roles Conceptualization, Writing – original draft, Writing – review & editing

  Affiliation Dana-Farber/Brigham and Women’s Cancer Center, Harvard Medical School, Dana-Farber Cancer Institute-Brigham and Women’s Hospital, Boston, Massachusetts, United States of America

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• Josien P. W. Pluim,

  Roles Funding acquisition, Methodology, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Medical Image Analysis Group, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands

  ⨯
• Rulla M. Tamimi,

  Roles Conceptualization, Data curation, Funding acquisition, Project administration, Writing – original draft, Writing – review & editing

  Affiliation Channing Division of Network Medicine, Department of Medicine, Harvard Medical School, Brigham and Women’s Hospital, Boston, Massachusetts, United States of America

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• Yujing J. Heng ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

  ¶‡ These authors are co-senior authors on this work.

  Affiliation Department of Pathology, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America

  http://orcid.org/0000-0002-8930-817X

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•  [ ... ],
• Mitko Veta

  Roles Conceptualization, Funding acquisition, Methodology, Supervision, Writing – original draft, Writing – review & editing

  ¶‡ These authors are co-senior authors on this work.

  Affiliation Medical Image Analysis Group, Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands

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