REG-O3 chimeric peptide combining growth hormone and somatostatin sequences improves joint function and prevents cartilage degradation in rat model of traumatic knee osteoarthritis

• Rodrick Montjean,

  Roles Supervision, Writing – original draft, Writing – review & editing

  Affiliation Regulaxis SAS, Romainville, France

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• Sonia Escaich,

  Roles Supervision, Writing – review & editing

  Affiliations Regulaxis SAS, Romainville, France, ESE Conseil, Saint-Cloud, France

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• Raffaello Paolini,

  Roles Conceptualization, Formal analysis, Writing – review & editing

  Affiliation Regulaxis SAS, Romainville, France

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• Claude Carelli,

  Roles Conceptualization, Funding acquisition, Project administration, Writing – review & editing

  Affiliation Regulaxis SAS, Romainville, France

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• Sébastien Pirson,

  Roles Conceptualization, Formal analysis, Investigation, Validation, Writing – original draft, Writing – review & editing

  Affiliation Artialis SA, Tour GIGA, CHU Sart-Tilman, Liège, Belgium

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• Thibaut Neutelings,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Validation, Writing – original draft, Writing – review & editing

  Affiliation Artialis SA, Tour GIGA, CHU Sart-Tilman, Liège, Belgium

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• Yves Henrotin ,

  Roles Conceptualization, Formal analysis, Methodology, Supervision, Writing – original draft

  * E-mail: yhenrotin@uliege.be

  Affiliations Artialis SA, Tour GIGA, CHU Sart-Tilman, Liège, Belgium, Bone and Cartilage Research Unit, Arthropôle Liège, University of Liège, Liège, Belgium, Physical Therapy and Rehabilitation Department, Princess Paola Hospital, Vivalia, Marche-en-Famenne, Belgium

  http://orcid.org/0000-0002-2846-4398

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• Christelle Vêtu

  Roles Conceptualization, Project administration, Supervision, Writing – review & editing

  Affiliation Regulaxis SAS, Romainville, France

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