Number of MRI T1-hypointensity corrected by T2/FLAIR lesion volume indicates clinical severity in patients with multiple sclerosis

• Tetsuya Akaishi ,

  Roles Conceptualization, Software, Visualization, Writing – original draft

  * E-mail: t-akaishi@med.tohoku.ac.jp

  Affiliations Department of Neurology, Tohoku University Graduate School of Medicine, Sendai, Japan, Department of Education and Support for Regional Medicine, Tohoku University Hospital, Sendai, Japan

  http://orcid.org/0000-0001-6728-4966

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• Toshiyuki Takahashi,

  Roles Conceptualization, Data curation, Investigation, Methodology, Writing – original draft

  Affiliations Department of Neurology, Tohoku University Graduate School of Medicine, Sendai, Japan, Department of Neurology, National Hospital Organization Yonezawa National Hospital, Yonezawa, Japan

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• Kazuo Fujihara,

  Roles Data curation, Methodology, Supervision, Writing – review & editing

  Affiliation Department of Multiple Sclerosis Therapeutics, Fukushima Medical University School of Medicine, Fukushima, Japan

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• Tatsuro Misu,

  Roles Conceptualization, Investigation, Methodology, Validation, Writing – review & editing

  Affiliation Department of Neurology, Tohoku University Graduate School of Medicine, Sendai, Japan

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• Shunji Mugikura,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Diagnostic Radiology, Tohoku University Graduate School of Medicine, Sendai, Japan

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• Michiaki Abe,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Education and Support for Regional Medicine, Tohoku University Hospital, Sendai, Japan

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• Tadashi Ishii,

  Roles Methodology, Writing – review & editing

  Affiliation Department of Education and Support for Regional Medicine, Tohoku University Hospital, Sendai, Japan

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• Masashi Aoki,

  Roles Project administration, Supervision, Writing – review & editing

  Affiliation Department of Neurology, Tohoku University Graduate School of Medicine, Sendai, Japan

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• Ichiro Nakashima

  Roles Conceptualization, Data curation, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  Affiliation Department of Neurology, Tohoku Medical and Pharmaceutical University, Sendai, Japan

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