No evidence for an association of plasma homocysteine levels and refractive error – Results from the population-based Gutenberg Health Study (GHS)

• Stefan Nickels ,

  Contributed equally to this work with: Stefan Nickels, Henk J. Blom

  Roles Conceptualization, Formal analysis, Investigation, Project administration, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: post@stefan-nickels.de

  Affiliation Department of Ophthalmology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany

  http://orcid.org/0000-0003-0415-2354

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• Henk J. Blom ,

  Contributed equally to this work with: Stefan Nickels, Henk J. Blom

  Roles Conceptualization, Investigation, Supervision, Writing – review & editing

  Affiliations Laboratory of Clinical Biochemistry and Metabolism, Department of General Pediatrics, Adolescent Medicine and Neonatology, University Medical Centre Freiburg, Freiburg, Germany, Metabolic Unit, Department of Clinical Genetics, Center for Lysosomal and Metabolic Diseases, ErasmusMC, Rotterdam, The Netherlands

  ⨯
• Andreas Schulz,

  Roles Conceptualization, Data curation, Investigation, Writing – review & editing

  Affiliation Preventive Cardiology and Preventive Medicine/Center for Cardiology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany

  ⨯
• Lutz Joachimsen,

  Roles Writing – review & editing

  Affiliation Eye Center, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany

  ⨯
• Thomas Münzel,

  Roles Conceptualization, Writing – review & editing

  Affiliations Center for Cardiology I, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany, Center for Translational Vascular Biology (CTVB), University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany

  ⨯
• Philipp S. Wild,

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliations Center for Cardiology I, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany, Center for Translational Vascular Biology (CTVB), University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany, Center for Thrombosis and Hemostasis (CTH), University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany, German Center for Cardiovascular Research (DZHK), partner site Rhine-Main, Mainz, Germany

  ⨯
• Manfred E. Beutel,

  Roles Conceptualization, Writing – review & editing

  Affiliation Department of Psychosomatic Medicine and Psychotherapy, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany

  ⨯
• Maria Blettner,

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliation Institute for Medical Biostatistics, Epidemiology and Informatics, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany

  ⨯
• Karl J. Lackner,

  Roles Conceptualization, Writing – review & editing

  Affiliation Institute for Clinical Chemistry and Laboratory Medicine, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany

  ⨯
• Norbert Pfeiffer ,

  Roles Conceptualization, Supervision, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation Department of Ophthalmology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz, Germany

  http://orcid.org/0000-0002-5766-2617

  ⨯
• Wolf A. Lagrèze

  Roles Conceptualization, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation Eye Center, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany

  ⨯