Image-based metric of invasiveness predicts response to adjuvant temozolomide for primary glioblastoma

• Susan Christine Massey ,

  Contributed equally to this work with: Susan Christine Massey, Haylye White, Paula Whitmire

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft

  * E-mail: Massey.Susan@mayo.edu

  Affiliation Mathematical NeuroOncology Laboratory, Precision Neurotherapeutics Innovation Program, Mayo Clinic, Phoenix, Arizona, United States of America

  http://orcid.org/0000-0002-4680-7796

  ⨯
• Haylye White ,

  Contributed equally to this work with: Susan Christine Massey, Haylye White, Paula Whitmire

  Roles Conceptualization, Investigation, Methodology, Software, Writing – review & editing

  Affiliation Mathematical NeuroOncology Laboratory, Precision Neurotherapeutics Innovation Program, Mayo Clinic, Phoenix, Arizona, United States of America

  ⨯
• Paula Whitmire ,

  Contributed equally to this work with: Susan Christine Massey, Haylye White, Paula Whitmire

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft

  Affiliation Mathematical NeuroOncology Laboratory, Precision Neurotherapeutics Innovation Program, Mayo Clinic, Phoenix, Arizona, United States of America

  ⨯
• Tatum Doyle,

  Roles Investigation, Writing – original draft

  Affiliations Mathematical NeuroOncology Laboratory, Precision Neurotherapeutics Innovation Program, Mayo Clinic, Phoenix, Arizona, United States of America, College of Literature, Science and the Arts, University of Michigan, Ann Arbor, Michigan, United States of America

  ⨯
• Sandra K. Johnston,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliations Mathematical NeuroOncology Laboratory, Precision Neurotherapeutics Innovation Program, Mayo Clinic, Phoenix, Arizona, United States of America, Department of Radiology, University of Washington, Seattle, Washington, United States of America

  ⨯
• Kyle W. Singleton,

  Roles Investigation, Software, Writing – review & editing

  Affiliation Mathematical NeuroOncology Laboratory, Precision Neurotherapeutics Innovation Program, Mayo Clinic, Phoenix, Arizona, United States of America

  http://orcid.org/0000-0002-9969-8474

  ⨯
• Pamela R. Jackson,

  Roles Data curation, Resources, Writing – review & editing

  Affiliation Mathematical NeuroOncology Laboratory, Precision Neurotherapeutics Innovation Program, Mayo Clinic, Phoenix, Arizona, United States of America

  http://orcid.org/0000-0002-8424-4007

  ⨯
• Andrea Hawkins-Daarud,

  Roles Investigation, Software, Writing – review & editing

  Affiliation Mathematical NeuroOncology Laboratory, Precision Neurotherapeutics Innovation Program, Mayo Clinic, Phoenix, Arizona, United States of America

  ⨯
• Bernard R. Bendok,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliations Department of Neurologic Surgery, Mayo Clinic, Phoenix, Arizona, United States of America, Department of Radiology, Mayo Clinic, Phoenix, Arizona, United States of America, Department of Otorhinolaryngology (ENT)/Head and Neck Surgery, Mayo Clinic, Phoenix, Arizona, United States of America, Neurosurgery Simulation and Innovation Laboratory, Precision Neurotherapeutics Innovation Program, Mayo Clinic, Phoenix, Arizona, United States of America

  ⨯
• Alyx B. Porter,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Department of Neurology, Mayo Clinic, Phoenix, Arizona, United States of America

  ⨯
• Sujay Vora,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Radiation Oncology, Mayo Clinic, Phoenix, Arizona, United States of America

  ⨯
• Jann N. Sarkaria,

  Roles Data curation, Funding acquisition, Investigation, Writing – review & editing

  Affiliation Department of Radiation Oncology, Mayo Clinic, Rochester, Minnesota, United States of America

  ⨯
• Leland S. Hu,

  Roles Data curation, Funding acquisition, Investigation, Resources, Writing – review & editing

  Affiliation Department of Radiology, Mayo Clinic, Phoenix, Arizona, United States of America

  ⨯
• Maciej M. Mrugala,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Department of Neurology, Mayo Clinic, Phoenix, Arizona, United States of America

  ⨯
• Kristin R. Swanson

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Resources, Writing – review & editing

  Affiliations Mathematical NeuroOncology Laboratory, Precision Neurotherapeutics Innovation Program, Mayo Clinic, Phoenix, Arizona, United States of America, Department of Neurologic Surgery, Mayo Clinic, Phoenix, Arizona, United States of America, School of Mathematical and Statistical Sciences, Arizona State University, Tempe, Arizona, United States of America

  ⨯