Genetic loci associated with prevalent and incident myocardial infarction and coronary heart disease in the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium

• Julie Hahn ,

  Contributed equally to this work with: Julie Hahn, Yi-Ping Fu, Michael R. Brown, Joshua C. Bis, Paul S. de Vries, Mary F. Feitosa, Lisa R. Yanek, Stefan Weiss, Franco Giulianini, Albert Vernon Smith, Xiuqing Guo

  Roles Writing – original draft

  * E-mail: Alanna.C.Morrison@uth.tmc.edu (ACM); Julie.M.Hahn@uth.tmc.edu (JH)

  Affiliation Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America

  https://orcid.org/0000-0002-9757-1648

  ⨯
• Yi-Ping Fu ,

  Contributed equally to this work with: Julie Hahn, Yi-Ping Fu, Michael R. Brown, Joshua C. Bis, Paul S. de Vries, Mary F. Feitosa, Lisa R. Yanek, Stefan Weiss, Franco Giulianini, Albert Vernon Smith, Xiuqing Guo

  Roles Conceptualization, Data curation, Formal analysis, Writing – original draft

  Affiliations Office of Biostatistics Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland, United States of America, Framingham Heart Study, National Heart, Lung, and Blood Institute, National Institutes of Health, Framingham, Massachusetts, United States of America

  ⨯
• Michael R. Brown ,

  Contributed equally to this work with: Julie Hahn, Yi-Ping Fu, Michael R. Brown, Joshua C. Bis, Paul S. de Vries, Mary F. Feitosa, Lisa R. Yanek, Stefan Weiss, Franco Giulianini, Albert Vernon Smith, Xiuqing Guo

  Roles Formal analysis

  Affiliation Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America

  https://orcid.org/0000-0002-5235-9037

  ⨯
• Joshua C. Bis ,

  Contributed equally to this work with: Julie Hahn, Yi-Ping Fu, Michael R. Brown, Joshua C. Bis, Paul S. de Vries, Mary F. Feitosa, Lisa R. Yanek, Stefan Weiss, Franco Giulianini, Albert Vernon Smith, Xiuqing Guo

  Roles Conceptualization, Formal analysis, Writing – original draft

  Affiliation Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, United States of America

  ⨯
• Paul S. de Vries ,

  Contributed equally to this work with: Julie Hahn, Yi-Ping Fu, Michael R. Brown, Joshua C. Bis, Paul S. de Vries, Mary F. Feitosa, Lisa R. Yanek, Stefan Weiss, Franco Giulianini, Albert Vernon Smith, Xiuqing Guo

  Roles Formal analysis, Writing – review & editing

  Affiliations Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands

  ⨯
• Mary F. Feitosa ,

  Contributed equally to this work with: Julie Hahn, Yi-Ping Fu, Michael R. Brown, Joshua C. Bis, Paul S. de Vries, Mary F. Feitosa, Lisa R. Yanek, Stefan Weiss, Franco Giulianini, Albert Vernon Smith, Xiuqing Guo

  Roles Formal analysis, Writing – review & editing

  Affiliation Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, United States of America

  https://orcid.org/0000-0002-0933-2410

  ⨯
• Lisa R. Yanek ,

  Contributed equally to this work with: Julie Hahn, Yi-Ping Fu, Michael R. Brown, Joshua C. Bis, Paul S. de Vries, Mary F. Feitosa, Lisa R. Yanek, Stefan Weiss, Franco Giulianini, Albert Vernon Smith, Xiuqing Guo

  Roles Formal analysis, Writing – review & editing

  Affiliation GeneSTAR Research Program, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

  https://orcid.org/0000-0001-7117-1075

  ⨯
• Stefan Weiss ,

  Contributed equally to this work with: Julie Hahn, Yi-Ping Fu, Michael R. Brown, Joshua C. Bis, Paul S. de Vries, Mary F. Feitosa, Lisa R. Yanek, Stefan Weiss, Franco Giulianini, Albert Vernon Smith, Xiuqing Guo

  Roles Formal analysis, Writing – review & editing

  Affiliations Interfaculty Institute for Genetics and Functional Genomics, The University Medicine and Ernst-Moritz-Arndt-University Greifswald, Greifswald, Germany, DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany

  https://orcid.org/0000-0002-3553-4315

  ⨯
• Franco Giulianini ,

  Contributed equally to this work with: Julie Hahn, Yi-Ping Fu, Michael R. Brown, Joshua C. Bis, Paul S. de Vries, Mary F. Feitosa, Lisa R. Yanek, Stefan Weiss, Franco Giulianini, Albert Vernon Smith, Xiuqing Guo

  Roles Formal analysis

  Affiliation Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, United States of America

  ⨯
• Albert Vernon Smith ,

  Contributed equally to this work with: Julie Hahn, Yi-Ping Fu, Michael R. Brown, Joshua C. Bis, Paul S. de Vries, Mary F. Feitosa, Lisa R. Yanek, Stefan Weiss, Franco Giulianini, Albert Vernon Smith, Xiuqing Guo

  Roles Formal analysis

  Affiliations Icelandic Heart Association, Kovapvogur, Iceland, Faculty of Medicine, University of Iceland, Reykajvik, Iceland

  https://orcid.org/0000-0003-1942-5845

  ⨯
• Xiuqing Guo ,

  Contributed equally to this work with: Julie Hahn, Yi-Ping Fu, Michael R. Brown, Joshua C. Bis, Paul S. de Vries, Mary F. Feitosa, Lisa R. Yanek, Stefan Weiss, Franco Giulianini, Albert Vernon Smith, Xiuqing Guo

  Roles Conceptualization, Formal analysis, Writing – review & editing

  Affiliation The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California, United States of America

  ⨯
• Traci M. Bartz,

  Roles Data curation, Writing – review & editing

  Affiliations Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, United States of America, Department of Biostatistics, The University of Washington, Seattle, Washington, United States of America

  ⨯
• Diane M. Becker,

  Roles Conceptualization, Data curation, Funding acquisition, Writing – review & editing

  Affiliation GeneSTAR Research Program, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

  ⨯
• Lewis C. Becker,

  Roles Conceptualization, Data curation, Funding acquisition, Writing – review & editing

  Affiliation GeneSTAR Research Program, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

  ⨯
• Eric Boerwinkle,

  Roles Conceptualization, Funding acquisition, Writing – review & editing

  Affiliations Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America, Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, United States of America

  ⨯
• Jennifer A. Brody,

  Roles Data curation, Formal analysis, Writing – original draft

  Affiliation Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, United States of America

  ⨯
• Yii-Der Ida Chen,

  Roles Data curation, Funding acquisition, Writing – original draft, Writing – review & editing

  Affiliation The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California, United States of America

  ⨯
• Oscar H. Franco,

  Roles Data curation, Funding acquisition, Writing – review & editing

  Affiliation Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands

  ⨯
• Megan Grove,

  Roles Data curation

  Affiliation Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America

  ⨯
• Tamara B. Harris,

  Roles Conceptualization, Funding acquisition

  Affiliation Laboratory of Epidemiology and Population Sciences, Intramural Research Program, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, United States of America

  ⨯
• Albert Hofman,

  Roles Conceptualization, Data curation, Funding acquisition, Writing – review & editing

  Affiliations Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom

  ⨯
• Shih-Jen Hwang,

  Roles Writing – review & editing

  Affiliation Framingham Heart Study, National Heart, Lung, and Blood Institute, National Institutes of Health, Framingham, Massachusetts, United States of America

  ⨯
• Brian G. Kral,

  Roles Data curation, Writing – review & editing

  Affiliation GeneSTAR Research Program, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

  ⨯
• Lenore J. Launer,

  Roles Conceptualization, Funding acquisition

  Affiliation Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands

  ⨯
• Marcello R. P. Markus,

  Roles Data curation, Writing – review & editing

  Affiliations DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany, Department of Internal Medicine B - Cardiology, Pneumology, Infectious Diseases, Intensive Care Medicine, The University Medicine Greifswald, Greifswald, Germany

  ⨯
• Kenneth M. Rice,

  Roles Conceptualization, Formal analysis, Writing – review & editing

  Affiliation Department of Biostatistics, The University of Washington, Seattle, Washington, United States of America

  https://orcid.org/0000-0002-3071-7278

  ⨯
• Stephen S. Rich,

  Roles Conceptualization, Funding acquisition, Writing – review & editing

  Affiliation Department of Medicine and Epidemiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

  ⨯
• Paul M. Ridker,

  Roles Conceptualization, Data curation, Funding acquisition, Writing – review & editing

  Affiliations Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Fernando Rivadeneira,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands

  https://orcid.org/0000-0001-9435-9441

  ⨯
• Jerome I. Rotter,

  Roles Conceptualization, Funding acquisition, Writing – review & editing

  Affiliation The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California, United States of America

  ⨯
• Nona Sotoodehnia,

  Roles Conceptualization, Writing – review & editing

  Affiliation Division of Cardiology, Department of Medicine, University of Washington, Seattle, Washington, United States of America

  ⨯
• Kent D. Taylor,

  Roles Data curation, Writing – review & editing

  Affiliation The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California, United States of America

  ⨯
• André G. Uitterlinden,

  Roles Data curation, Funding acquisition, Writing – review & editing

  Affiliations Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America

  ⨯
• Uwe Völker,

  Roles Conceptualization, Data curation, Writing – review & editing

  Affiliations Interfaculty Institute for Genetics and Functional Genomics, The University Medicine and Ernst-Moritz-Arndt-University Greifswald, Greifswald, Germany, DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany

  ⨯
• Henry Völzke,

  Roles Conceptualization, Data curation, Writing – review & editing

  Affiliations DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany, Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany

  ⨯
• Jie Yao,

  Roles Formal analysis

  Affiliation The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, California, United States of America

  ⨯
• Daniel I. Chasman,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Writing – review & editing

  Affiliations Division of Preventive Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Marcus Dörr,

  Roles Data curation, Writing – review & editing

  Affiliations DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany, Department of Internal Medicine B - Cardiology, Pneumology, Infectious Diseases, Intensive Care Medicine, The University Medicine Greifswald, Greifswald, Germany

  ⨯
• Vilmundur Gudnason,

  Roles Conceptualization, Data curation, Funding acquisition

  Affiliations Icelandic Heart Association, Kovapvogur, Iceland, Faculty of Medicine, University of Iceland, Reykajvik, Iceland

  https://orcid.org/0000-0001-5696-0084

  ⨯
• Rasika A. Mathias,

  Roles Data curation, Funding acquisition, Writing – review & editing

  Affiliation GeneSTAR Research Program, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

  ⨯
• Wendy Post,

  Roles Conceptualization, Data curation, Funding acquisition, Writing – review & editing

  Affiliation Department of Medicine and Epidemiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

  ⨯
• Bruce M. Psaty,

  Roles Conceptualization, Data curation, Funding acquisition, Writing – original draft

  Affiliations Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, United States of America, Department of Epidemiology, The University of Washington, Seattle, Washington, United States of America, Department of Health Services, The University of Washington, Seattle, Washington, United States of America, Kaiser Permanente Research Institute, Seattle, Washington, United States of America

  ⨯
• Abbas Dehghan,

  Roles Formal analysis, Writing – review & editing

  Affiliations Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Epidemiology and Biostatistics, Imperial College London, London, United Kingdom

  ⨯
• Christopher J. O’Donnell ,

  Roles Conceptualization, Writing – review & editing

  ¶‡ CJO and ACM also contributed equally to this work.

  Affiliations Framingham Heart Study, National Heart, Lung, and Blood Institute, National Institutes of Health, Framingham, Massachusetts, United States of America, Harvard Medical School, Boston, Massachusetts, United States of America, VA Boston Healthcare System, Veteran’s Affair, Boston, Massachusetts, United States of America, Cardiovascular Medicine Division, Brigham and Women’s Hospital, Boston, Massachusetts, United States of America

  ⨯
•  [ ... ],
• Alanna C. Morrison

  Roles Conceptualization, Data curation, Formal analysis, Writing – review & editing

  * E-mail: Alanna.C.Morrison@uth.tmc.edu (ACM); Julie.M.Hahn@uth.tmc.edu (JH)

  ¶‡ CJO and ACM also contributed equally to this work.

  Affiliation Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America

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