Cell-free IgG-aggregates in plasma of patients with chronic lymphocytic leukemia cause chronic activation of the classical complement pathway

• Regina Michelis ,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: ReginaM@gmc.gov.il

  Affiliation The Institute for Medical Research, Galilee Medical Center, Nahariya, Israel

  http://orcid.org/0000-0002-3513-9016

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• Tamar Tadmor,

  Roles Conceptualization, Resources

  Affiliations Hematology Division, Bnai Zion Medical Center, Haifa, Israel, The Ruth and Bruce Rappaport Faculty of Medicine, Technion, Haifa, Israel

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• Ariel Aviv,

  Roles Conceptualization, Resources, Validation

  Affiliation Department of Hematology, Emek Medical Center, Afula, Israel

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• Galia Stemer,

  Roles Resources

  Affiliation Department of Hematology, Emek Medical Center, Afula, Israel

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• Rawan Majdob,

  Roles Data curation, Methodology

  Affiliation The Institute for Medical Research, Galilee Medical Center, Nahariya, Israel

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• Lev Shvidel,

  Roles Data curation, Resources

  Affiliations Hematology Institute, Kaplan Medical Center, Rehovot, Israel, Faculty of Medicine, Hebrew University, Jerusalem, Israel

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• Mona Shehadeh,

  Roles Data curation

  Affiliation Biochemistry Laboratory, Galilee Medical Center, Nahariya, Israel

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• Masad Barhoum ,

  Contributed equally to this work with: Masad Barhoum, Andrei Braester

  Roles Resources, Supervision

  Affiliations Institute of Hematology, Galilee Medical Center, Nahariya, Israel, Azrieli Faculty of Medicine, Bar Ilan University, Safed, Israel

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• Andrei Braester

  Contributed equally to this work with: Masad Barhoum, Andrei Braester

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision

  Affiliations Institute of Hematology, Galilee Medical Center, Nahariya, Israel, Azrieli Faculty of Medicine, Bar Ilan University, Safed, Israel

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