Nanosecond pulsed electric fields induce the integrated stress response via reactive oxygen species-mediated heme-regulated inhibitor (HRI) activation

• Yoshimasa Hamada,

  Roles Formal analysis, Investigation, Writing – original draft

  Affiliations Division of Molecular Biology, Institute for Genome Research, Institute of Advanced Medical Sciences, Tokushima University, Tokushima, Japan, Fujii Memorial Institute of Medical Sciences, Institute of Advanced Medical Sciences, Tokushima University, Tokushima, Japan

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• Yuji Furumoto,

  Roles Investigation, Methodology

  Affiliation Institute of Technology and Science, Tokushima University, Tokushima, Japan

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• Akira Izutani,

  Roles Investigation, Methodology

  Affiliation Institute of Technology and Science, Tokushima University, Tokushima, Japan

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• Shusuke Taniuchi,

  Roles Investigation, Resources

  Affiliations Division of Molecular Biology, Institute for Genome Research, Institute of Advanced Medical Sciences, Tokushima University, Tokushima, Japan, Fujii Memorial Institute of Medical Sciences, Institute of Advanced Medical Sciences, Tokushima University, Tokushima, Japan, Department of Molecular Physiology, Diabetes Therapeutics and Research Center, Institute of Advanced Medical Sciences, Tokushima University, Tokushima, Japan

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• Masato Miyake,

  Roles Investigation, Supervision

  Affiliations Division of Molecular Biology, Institute for Genome Research, Institute of Advanced Medical Sciences, Tokushima University, Tokushima, Japan, Fujii Memorial Institute of Medical Sciences, Institute of Advanced Medical Sciences, Tokushima University, Tokushima, Japan, Department of Molecular Physiology, Diabetes Therapeutics and Research Center, Institute of Advanced Medical Sciences, Tokushima University, Tokushima, Japan

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• Miho Oyadomari,

  Roles Data curation, Project administration

  Affiliation Division of Molecular Biology, Institute for Genome Research, Institute of Advanced Medical Sciences, Tokushima University, Tokushima, Japan

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• Kenji Teranishi,

  Roles Methodology

  Affiliation Institute of Technology and Science, Tokushima University, Tokushima, Japan

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• Naoyuki Shimomura,

  Roles Methodology, Supervision

  Affiliation Institute of Technology and Science, Tokushima University, Tokushima, Japan

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• Seiichi Oyadomari

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: oyadomar@tokushima-u.ac.jp

  Affiliations Division of Molecular Biology, Institute for Genome Research, Institute of Advanced Medical Sciences, Tokushima University, Tokushima, Japan, Fujii Memorial Institute of Medical Sciences, Institute of Advanced Medical Sciences, Tokushima University, Tokushima, Japan, Department of Molecular Physiology, Diabetes Therapeutics and Research Center, Institute of Advanced Medical Sciences, Tokushima University, Tokushima, Japan

  http://orcid.org/0000-0001-6766-1485

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