Evaluation of antiviral T cell responses and TSCM cells in volunteers enrolled in a phase I HIV-1 subtype C prophylactic vaccine trial in India

Sivasankaran Munusamy Ponnan; Peter Hayes; Natalia Fernandez; Kannan Thiruvengadam; Sathyamurthi Pattabiram; Manohar Nesakumar; Ashokkumar Srinivasan; Sujitha Kathirvel; Janani Shankar; Rajat Goyal; Nikhil Singla; Joyeeta Mukherjee; Shweta Chatrath; Jill Gilmour; Sudha Subramanyam; Srikanth Prasad Tripathy; Soumya Swaminathan; Luke Elizabeth Hanna

doi:10.1371/journal.pone.0229461

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Open Access

Peer-reviewed

Research Article

Evaluation of antiviral T cell responses and T_SCM cells in volunteers enrolled in a phase I HIV-1 subtype C prophylactic vaccine trial in India

Sivasankaran Munusamy Ponnan,

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation National Institute for Research in Tuberculosis (Indian Council of Medical Research), Chennai, India
⨯
Peter Hayes,

Roles Conceptualization, Formal analysis, Methodology, Supervision, Validation, Writing – review & editing

Affiliation IAVI Human Immunology Laboratory, Imperial College, London, England, United Kingdom
⨯
Natalia Fernandez,

Roles Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliation IAVI Human Immunology Laboratory, Imperial College, London, England, United Kingdom
⨯
Kannan Thiruvengadam,

Roles Data curation, Formal analysis, Software

Affiliation National Institute for Research in Tuberculosis (Indian Council of Medical Research), Chennai, India
⨯
Sathyamurthi Pattabiram,

Roles Investigation

Affiliation National Institute for Research in Tuberculosis (Indian Council of Medical Research), Chennai, India
⨯
Manohar Nesakumar,

Roles Investigation

Affiliation National Institute for Research in Tuberculosis (Indian Council of Medical Research), Chennai, India
⨯
Ashokkumar Srinivasan,

Roles Data curation, Formal analysis, Investigation, Methodology

Affiliation National Institute for Research in Tuberculosis (Indian Council of Medical Research), Chennai, India
⨯
Sujitha Kathirvel,

Roles Data curation, Formal analysis, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing

Affiliation National Institute for Research in Tuberculosis (Indian Council of Medical Research), Chennai, India
⨯
Janani Shankar,

Roles Data curation, Formal analysis, Methodology, Resources

Affiliation National Institute for Research in Tuberculosis (Indian Council of Medical Research), Chennai, India
⨯
Rajat Goyal,

Roles Formal analysis, Funding acquisition, Project administration

Affiliation International AIDS Vaccine Initiative, New Delhi, India
⨯
Nikhil Singla,

Roles Formal analysis, Funding acquisition, Investigation, Methodology, Resources, Supervision

Affiliation International AIDS Vaccine Initiative, New Delhi, India
⨯
Joyeeta Mukherjee,

Roles Funding acquisition, Methodology, Project administration, Supervision

Affiliation International AIDS Vaccine Initiative, New Delhi, India
⨯
Shweta Chatrath,

Roles Funding acquisition, Investigation, Project administration, Resources, Supervision

Affiliation International AIDS Vaccine Initiative, New Delhi, India
⨯
Jill Gilmour,

Roles Funding acquisition, Investigation

Affiliation IAVI Human Immunology Laboratory, Imperial College, London, England, United Kingdom
⨯
Sudha Subramanyam,

Roles Funding acquisition, Investigation, Methodology

Affiliation National Institute for Research in Tuberculosis (Indian Council of Medical Research), Chennai, India
⨯
Srikanth Prasad Tripathy,

Roles Funding acquisition, Investigation

Affiliation National Institute for Research in Tuberculosis (Indian Council of Medical Research), Chennai, India
⨯
Soumya Swaminathan,

Roles Conceptualization, Funding acquisition, Investigation

Affiliation National Institute for Research in Tuberculosis (Indian Council of Medical Research), Chennai, India
⨯
[ ... ],
Luke Elizabeth Hanna

Roles Conceptualization, Funding acquisition, Investigation, Supervision, Writing – original draft, Writing – review & editing

* E-mail: hanna@nirt.res.in

Current address: Department of HIV/AIDS, National Institute for Research in Tuberculosis, Chennai, India

Affiliation National Institute for Research in Tuberculosis (Indian Council of Medical Research), Chennai, India

http://orcid.org/0000-0002-6299-8211

⨯
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Evaluation of antiviral T cell responses and T_SCM cells in volunteers enrolled in a phase I HIV-1 subtype C prophylactic vaccine trial in India

Sivasankaran Munusamy Ponnan,
Peter Hayes,
Natalia Fernandez,
Kannan Thiruvengadam,
Sathyamurthi Pattabiram,
Manohar Nesakumar,
Ashokkumar Srinivasan,
Sujitha Kathirvel,
Janani Shankar,
Rajat Goyal

Published: February 25, 2020
https://doi.org/10.1371/journal.pone.0229461

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