Proteolysis and cartilage development are activated in the synovium after surgical induction of post traumatic osteoarthritis

• Ugur M. Ayturk ,

  Contributed equally to this work with: Ugur M. Ayturk, Jakob T. Sieker, Carla M. Haslauer

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Writing – original draft, Writing – review & editing

  Affiliations Department of Orthopaedic Surgery, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

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• Jakob T. Sieker ,

  Contributed equally to this work with: Ugur M. Ayturk, Jakob T. Sieker, Carla M. Haslauer

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Orthopaedic Surgery, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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• Carla M. Haslauer ,

  Contributed equally to this work with: Ugur M. Ayturk, Jakob T. Sieker, Carla M. Haslauer

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Project administration, Writing – review & editing

  Affiliation Department of Orthopaedic Surgery, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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• Benedikt L. Proffen,

  Roles Conceptualization, Data curation, Investigation, Methodology, Project administration, Writing – review & editing

  Affiliation Department of Orthopaedic Surgery, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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• Manuela H. Weissenberger,

  Roles Conceptualization, Data curation, Investigation, Writing – review & editing

  Affiliation Department of Pathology, Caritas-Hospital Bad Mergentheim, Bad Mergentheim, Germany

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• Matthew L. Warman,

  Roles Conceptualization, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  Affiliations Department of Orthopaedic Surgery, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

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• Braden C. Fleming,

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  Affiliation Department of Orthopaedics, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island, United States of America

  http://orcid.org/0000-0002-7841-425X

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• Martha M. Murray

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: Martha.Murray@childrens.harvard.edu

  Affiliation Department of Orthopaedic Surgery, Boston Children’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

  http://orcid.org/0000-0001-5086-9511

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