Contribution of Leishmania braziliensis antigen-specific CD4⁺ T, CD8⁺ T, NK and CD3⁺CD56⁺NKT cells in the immunopathogenesis of cutaneous leishmaniasis patients: Cytotoxic, activation and exhaustion profiles

• Clarissa F. Cunha,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

  Current address: Hematology and Oncology Unit, Hospital of Federal University of Juiz de Fora, Juiz de Fora, Minas Gerais, Brazil

  Affiliation Laboratory of Immunoparasitology, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, Rio de Janeiro, Brazil

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• Raquel Ferraz-Nogueira,

  Roles Investigation, Methodology, Supervision

  Current address: Beckman Coulter Life Sciences, São Paulo, São Paulo, Brazil

  Affiliations Laboratory of Immunoparasitology, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, Rio de Janeiro, Brazil, Flow Cytometry Core Facility, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, Rio de Janeiro, Brazil

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• Vanessa F. A. Costa,

  Roles Investigation, Methodology

  Affiliations Laboratory of Immunoparasitology, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, Rio de Janeiro, Brazil, Flow Cytometry Core Facility, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, Rio de Janeiro, Brazil

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• Maria Inês F. Pimentel,

  Roles Methodology, Validation

  Affiliation Laboratory of Surveillance for Leishmaniasis, Evandro Chagas National Institute of Infectology, FIOCRUZ, Rio de Janeiro, Rio de Janeiro, Brazil

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• Thaize Q. Chometon,

  Roles Data curation, Formal analysis, Methodology, Writing – review & editing

  Affiliation Flow Cytometry Core Facility, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, Rio de Janeiro, Brazil

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• Marcelo R. Lyra,

  Roles Methodology, Validation

  Affiliation Laboratory of Surveillance for Leishmaniasis, Evandro Chagas National Institute of Infectology, FIOCRUZ, Rio de Janeiro, Rio de Janeiro, Brazil

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• Armando O. Schubach,

  Roles Methodology, Validation

  Affiliation Laboratory of Surveillance for Leishmaniasis, Evandro Chagas National Institute of Infectology, FIOCRUZ, Rio de Janeiro, Rio de Janeiro, Brazil

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• Alda Maria Da-Cruz,

  Roles Methodology, Supervision, Validation, Writing – review & editing

  Affiliation Laboratory of Interdisciplinary Medical Research, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, Rio de Janeiro, Brazil

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• Alvaro Luiz Bertho

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Supervision, Validation, Writing – review & editing

  * E-mail: alvaro.bertho@ioc.fiocruz.br

  Affiliations Laboratory of Immunoparasitology, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, Rio de Janeiro, Brazil, Flow Cytometry Core Facility, Oswaldo Cruz Institute, FIOCRUZ, Rio de Janeiro, Rio de Janeiro, Brazil

  http://orcid.org/0000-0002-0962-1925

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