Human and mouse activin genes: Divergent expression of activin A protein variants and identification of a novel heparan sulfate-binding domain in activin B

Paul C. Billings; Candice Bizzaro; Evan Yang; Juliet Chung; Christina Mundy; Maurizio Pacifici

doi:10.1371/journal.pone.0229254

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Peer-reviewed

Research Article

Human and mouse activin genes: Divergent expression of activin A protein variants and identification of a novel heparan sulfate-binding domain in activin B

Paul C. Billings ,

Roles Conceptualization, Data curation, Formal analysis, Methodology, Supervision, Writing – original draft

* E-mail: BillingsP@email.chop.edu

Affiliation Translational Research Program in Pediatric Orthopaedics, Division of Orthopaedic Surgery, The Children’s Hospital of Philadelphia, Philadelphia, PA, United States of America

http://orcid.org/0000-0002-1365-7664

⨯
Candice Bizzaro ,

Contributed equally to this work with: Candice Bizzaro, Evan Yang

Roles Data curation

Affiliation Translational Research Program in Pediatric Orthopaedics, Division of Orthopaedic Surgery, The Children’s Hospital of Philadelphia, Philadelphia, PA, United States of America
⨯
Evan Yang ,

Contributed equally to this work with: Candice Bizzaro, Evan Yang

Roles Data curation, Formal analysis

Current address: Graduate Program in Biological and Biomedical Sciences (BBS), Harvard Medical School, Boston, MA, United States of America

Affiliation Translational Research Program in Pediatric Orthopaedics, Division of Orthopaedic Surgery, The Children’s Hospital of Philadelphia, Philadelphia, PA, United States of America
⨯
Juliet Chung,

Roles Data curation

Affiliation Translational Research Program in Pediatric Orthopaedics, Division of Orthopaedic Surgery, The Children’s Hospital of Philadelphia, Philadelphia, PA, United States of America
⨯
Christina Mundy,

Roles Data curation, Formal analysis, Methodology, Supervision

Affiliation Translational Research Program in Pediatric Orthopaedics, Division of Orthopaedic Surgery, The Children’s Hospital of Philadelphia, Philadelphia, PA, United States of America
⨯
Maurizio Pacifici

Roles Conceptualization, Funding acquisition, Supervision

Affiliation Translational Research Program in Pediatric Orthopaedics, Division of Orthopaedic Surgery, The Children’s Hospital of Philadelphia, Philadelphia, PA, United States of America
⨯

Human and mouse activin genes: Divergent expression of activin A protein variants and identification of a novel heparan sulfate-binding domain in activin B

Paul C. Billings,
Candice Bizzaro,
Evan Yang,
Juliet Chung,
Christina Mundy,
Maurizio Pacifici

Published: February 19, 2020
https://doi.org/10.1371/journal.pone.0229254

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Polymerase chain reaction
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Protein structure
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Transfection
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Extracellular matrix proteins
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Heparin
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Protein expression
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Protein structure prediction
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