Intranasal administration of dantrolene increased brain concentration and duration

• Jintao Wang ,

  Contributed equally to this work with: Jintao Wang, Yun Shi

  Roles Data curation, Formal analysis, Investigation

  Affiliations Department of Anesthesiology and Critical Care, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States of America, Department of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

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• Yun Shi ,

  Contributed equally to this work with: Jintao Wang, Yun Shi

  Roles Data curation, Formal analysis, Writing – original draft, Writing – review & editing

  Affiliations Department of Anesthesiology and Critical Care, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States of America, Department of Anesthesiology, Children’s Hospital of Fudan University, Shanghai, China

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• Shuchun Yu,

  Roles Data curation, Formal analysis

  Affiliations Department of Anesthesiology and Critical Care, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States of America, Department of Anesthesiology, The Second Affiliated Hospital to Nanchang University, Nanchang, Jiangxi, China

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• Yan Wang,

  Roles Data curation, Formal analysis

  Affiliations Department of Anesthesiology and Critical Care, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States of America, Department of Anesthesiology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China

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• Qingcheng Meng,

  Roles Data curation, Formal analysis

  Affiliation Department of Anesthesiology and Critical Care, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States of America

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• Ge Liang,

  Roles Data curation, Writing – original draft, Writing – review & editing

  Affiliation Department of Anesthesiology and Critical Care, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States of America

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• Maryellen F. Eckenhoff,

  Roles Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Department of Anesthesiology and Critical Care, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States of America

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• Huafeng Wei

  Roles Conceptualization, Formal analysis, Funding acquisition, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: weih@uphs.upenn.edu

  Affiliation Department of Anesthesiology and Critical Care, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, United States of America

  http://orcid.org/0000-0002-5634-8378

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