Repeated sleep disruption in mice leads to persistent shifts in the fecal microbiome and metabolome

• Samuel J. Bowers ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Resources, Software, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: samuel.bowers@northwestern.edu

  Affiliations Center for Sleep and Circadian Biology, Northwestern University, Evanston, Illinois, United States of America, Department of Neurobiology, Northwestern University, Evanston, Illinois, United States of America

  http://orcid.org/0000-0002-4821-699X

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• Fernando Vargas,

  Roles Data curation, Formal analysis, Investigation, Resources, Software, Writing – review & editing

  Affiliation Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy & Pharmaceutical Sciences, University of California San Diego, La Jolla, California, United States of America

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• Antonio González,

  Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Software, Writing – review & editing

  Affiliation Department of Pediatrics, University of California San Diego School of Medicine, La Jolla, California, United States of America

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• Shannon He,

  Roles Investigation, Writing – review & editing

  Affiliations Center for Sleep and Circadian Biology, Northwestern University, Evanston, Illinois, United States of America, Department of Neurobiology, Northwestern University, Evanston, Illinois, United States of America

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• Peng Jiang,

  Roles Formal analysis, Investigation, Software, Writing – review & editing

  Affiliations Center for Sleep and Circadian Biology, Northwestern University, Evanston, Illinois, United States of America, Department of Neurobiology, Northwestern University, Evanston, Illinois, United States of America

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• Pieter C. Dorrestein,

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

  Affiliations Collaborative Mass Spectrometry Innovation Center, Skaggs School of Pharmacy & Pharmaceutical Sciences, University of California San Diego, La Jolla, California, United States of America, Center for Microbiome Innovation, University of California San Diego, La Jolla, California, United States of America

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• Rob Knight,

  Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – review & editing

  Affiliations Department of Pediatrics, University of California San Diego School of Medicine, La Jolla, California, United States of America, Center for Microbiome Innovation, University of California San Diego, La Jolla, California, United States of America, Department of Computer Science and Engineering, University of California San Diego, La Jolla, California, United States of America

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• Kenneth P. Wright Jr,

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  Affiliations Department of Integrative Physiology, University of Colorado Boulder, Boulder, Colorado, United States of America, Center for Neuroscience, University of Colorado Boulder, Boulder, Colorado, United States of America, Sleep and Chronobiology Laboratory, University of Colorado Boulder, Boulder, Colorado, United States of America

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• Christopher A. Lowry,

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  Affiliations Department of Integrative Physiology, University of Colorado Boulder, Boulder, Colorado, United States of America, Center for Neuroscience, University of Colorado Boulder, Boulder, Colorado, United States of America

  http://orcid.org/0000-0003-3920-5575

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• Monika Fleshner,

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  Affiliations Department of Integrative Physiology, University of Colorado Boulder, Boulder, Colorado, United States of America, Center for Neuroscience, University of Colorado Boulder, Boulder, Colorado, United States of America

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• Martha H. Vitaterna,

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

  Affiliations Center for Sleep and Circadian Biology, Northwestern University, Evanston, Illinois, United States of America, Department of Neurobiology, Northwestern University, Evanston, Illinois, United States of America

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• Fred W. Turek

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

  Affiliations Center for Sleep and Circadian Biology, Northwestern University, Evanston, Illinois, United States of America, Department of Neurobiology, Northwestern University, Evanston, Illinois, United States of America, The Ken & Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America, Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America

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