Safety and efficacy of hydroxyurea and eflornithine against most blood parasites Babesia and Theileria

• Gaber El-Saber Batiha ,

  Contributed equally to this work with: Gaber El-Saber Batiha, Amany Magdy Beshbishy

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Visualization, Writing – original draft

  Affiliations National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan, Department of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour, Al-Beheira, Egypt

  ⨯
• Amany Magdy Beshbishy ,

  Contributed equally to this work with: Gaber El-Saber Batiha, Amany Magdy Beshbishy

  Roles Conceptualization, Data curation, Formal analysis, Resources, Visualization, Writing – original draft

  Affiliation National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan

  ⨯
• Oluyomi Stephen Adeyemi,

  Roles Formal analysis, Resources, Writing – original draft

  Affiliation Department of Biochemistry, Medicinal Biochemistry, Nanomedicine and Toxicology Laboratory, Landmark University, Omu-Aran, Kwara State, Nigeria

  ⨯
• Eman Nadwa,

  Roles Resources

  Affiliations Department of Pharmacology and Therapeutics, College of Medicine, Jouf University, Jouf, Egypt, Department of Medical Pharmacology, Faculty of Medicine, Cairo University, Cario, Egypt

  ⨯
• Eman Rashwan,

  Roles Resources

  Affiliations Department of Physiology, College of Medicine, Al-Azhar University, Assuit, Egypt, Department of Physiology, College of Medicine, Jouf University, Sakaka, Saudi Arabia

  ⨯
• Naoaki Yokoyama,

  Roles Resources

  Affiliation National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan

  ⨯
• Ikuo Igarashi

  Roles Funding acquisition, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: igarcpmi@obihiro.ac.jp

  Affiliation National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan

  http://orcid.org/0000-0003-4361-3942

  ⨯