The threshold of alpha-fetoprotein (AFP) for the diagnosis of hepatocellular carcinoma: A systematic review and meta-analysis

Jiaxin Zhang; Guang Chen; Peng Zhang; Jiaying Zhang; Xiaoke Li; Da’nan Gan; Xu Cao; Mei Han; Hongbo Du; Yong’an Ye

doi:10.1371/journal.pone.0228857

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Open Access

Peer-reviewed

Research Article

The threshold of alpha-fetoprotein (AFP) for the diagnosis of hepatocellular carcinoma: A systematic review and meta-analysis

Jiaxin Zhang ,

Contributed equally to this work with: Jiaxin Zhang, Guang Chen

Roles Conceptualization, Writing – original draft

Affiliations Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China, Institute of Liver Diseases, Beijing University of Chinese Medicine, Beijing, China
⨯
Guang Chen ,

Contributed equally to this work with: Jiaxin Zhang, Guang Chen

Roles Conceptualization, Formal analysis, Writing – original draft

Affiliations Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China, Institute of Liver Diseases, Beijing University of Chinese Medicine, Beijing, China
⨯
Peng Zhang,

Roles Data curation

Affiliations Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China, Institute of Liver Diseases, Beijing University of Chinese Medicine, Beijing, China
⨯
Jiaying Zhang,

Roles Formal analysis

Affiliation Ministry of Education Key Laboratory of Bioinformatics, Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China
⨯
Xiaoke Li,

Roles Formal analysis

Affiliations Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China, Institute of Liver Diseases, Beijing University of Chinese Medicine, Beijing, China
⨯
Da’nan Gan,

Roles Formal analysis

Affiliations Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China, Institute of Liver Diseases, Beijing University of Chinese Medicine, Beijing, China
⨯
Xu Cao,

Roles Data curation

Affiliations Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China, Institute of Liver Diseases, Beijing University of Chinese Medicine, Beijing, China

http://orcid.org/0000-0002-9566-6440

⨯
Mei Han,

Roles Methodology

Affiliation Center for Evidence-based Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China
⨯
Hongbo Du,

Roles Formal analysis

Affiliations Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China, Institute of Liver Diseases, Beijing University of Chinese Medicine, Beijing, China
⨯
Yong’an Ye

Roles Conceptualization

* E-mail: yeyongan@vip.163.com

Affiliations Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing, China, Institute of Liver Diseases, Beijing University of Chinese Medicine, Beijing, China

http://orcid.org/0000-0001-9765-4665

⨯

The threshold of alpha-fetoprotein (AFP) for the diagnosis of hepatocellular carcinoma: A systematic review and meta-analysis

Jiaxin Zhang,
Guang Chen,
Peng Zhang,
Jiaying Zhang,
Xiaoke Li,
Da’nan Gan,
Xu Cao,
Mei Han,
Hongbo Du,
Yong’an Ye

Published: February 13, 2020
https://doi.org/10.1371/journal.pone.0228857

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