Development and validation of a sensitive LC-MS/MS method for the quantitation of IMB-YH-4py5-2H, an antituberculosis candidate, and its application to the pharmacokinetic study

• Sen He,

  Roles Investigation, Methodology, Writing – original draft

  Affiliation Beijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

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• Hong-Tong Chen,

  Roles Investigation

  Affiliation Beijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

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• Rui Zhao,

  Roles Data curation

  Affiliation Beijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

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• Xin-Xin Hu,

  Roles Investigation

  Affiliation Beijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

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• Tong-Ying Nie,

  Roles Investigation

  Affiliation Beijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

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• Xin-Yi Yang,

  Roles Data curation

  Affiliation Beijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

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• Cong-Ran Li,

  Roles Writing – review & editing

  Affiliation Beijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

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• Xi Lu,

  Roles Writing – review & editing

  Affiliation Beijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

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• Xiu-Kun Wang,

  Roles Data curation

  Affiliation Beijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

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• Xue Li,

  Roles Investigation

  Affiliation Beijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

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• Yun Lu,

  Roles Investigation

  Affiliation Beijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

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• Guo-Qing Li,

  Roles Investigation

  Affiliation Beijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

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• Jing Pang ,

  Contributed equally to this work with: Jing Pang, Xue-Fu You

  Roles Conceptualization, Writing – review & editing

  * E-mail: pangjing.pangjing@163.com (JP); xuefuyou@imb.pumc.edu.cn (XY).

  Affiliation Beijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

  http://orcid.org/0000-0002-0538-0327

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• Xue-Fu You

  Contributed equally to this work with: Jing Pang, Xue-Fu You

  Roles Conceptualization, Writing – review & editing

  * E-mail: pangjing.pangjing@163.com (JP); xuefuyou@imb.pumc.edu.cn (XY).

  Affiliation Beijing Key Laboratory of Antimicrobial Agents, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China

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