The dipeptidyl peptidase-4 inhibitor, linagliptin, improves cognitive impairment in streptozotocin-induced diabetic mice by inhibiting oxidative stress and microglial activation

• Makoto Ide ,

  Contributed equally to this work with: Makoto Ide, Noriyuki Sonoda

  Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Internal Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

  ⨯
• Noriyuki Sonoda ,

  Contributed equally to this work with: Makoto Ide, Noriyuki Sonoda

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Project administration, Supervision, Writing – review & editing

  * E-mail: noriyuki@intmed3.med.kyushu-u.ac.jp

  Affiliations Department of Internal Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan, Innovation Center for Medical Redox Navigation, Kyushu University, Fukuoka, Japan

  http://orcid.org/0000-0003-0872-1606

  ⨯
• Tomoaki Inoue,

  Roles Formal analysis, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Internal Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

  ⨯
• Shinichiro Kimura,

  Roles Data curation, Formal analysis, Investigation, Methodology

  Affiliation Department of Internal Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

  ⨯
• Yohei Minami,

  Roles Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Internal Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

  ⨯
• Hiroaki Makimura,

  Roles Data curation, Formal analysis, Investigation

  Affiliation Department of Internal Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

  ⨯
• Eiichi Hayashida,

  Roles Formal analysis, Investigation, Visualization

  Affiliation Department of Internal Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

  ⨯
• Fuminori Hyodo,

  Roles Formal analysis, Methodology, Supervision, Visualization, Writing – review & editing

  Affiliation Innovation Center for Medical Redox Navigation, Kyushu University, Fukuoka, Japan

  ⨯
• Mayumi Yamato,

  Affiliation Innovation Center for Medical Redox Navigation, Kyushu University, Fukuoka, Japan

  ⨯
• Ryoichi Takayanagi,

  Roles Conceptualization, Project administration, Supervision

  Affiliation Department of Internal Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

  ⨯
• Toyoshi Inoguchi

  Roles Conceptualization, Project administration, Supervision

  Affiliations Innovation Center for Medical Redox Navigation, Kyushu University, Fukuoka, Japan, Fukuoka City Health Promotion Support Center, Fukuoka, Japan

  ⨯