Metabolic and lipidomic profiling of steatotic human livers during ex situ normothermic machine perfusion guides resuscitation strategies

• Siavash Raigani,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Division of Transplantation, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

  http://orcid.org/0000-0003-2762-7287

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• Negin Karimian,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology

  Affiliation Center for Engineering in Medicine, Massachusetts General Hospital and Shriners Hospital for Children, Boston, Massachusetts, United States of America

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• Viola Huang,

  Roles Conceptualization, Data curation, Investigation, Methodology

  Affiliation Center for Engineering in Medicine, Massachusetts General Hospital and Shriners Hospital for Children, Boston, Massachusetts, United States of America

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• Anna M. Zhang,

  Roles Data curation, Formal analysis, Investigation

  Affiliation Tufts University School of Medicine, Boston, Massachusetts, United States of America

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• Irene Beijert,

  Roles Data curation, Formal analysis, Investigation

  Affiliations Center for Engineering in Medicine, Massachusetts General Hospital and Shriners Hospital for Children, Boston, Massachusetts, United States of America, Section of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, University of Groningen, University Medical Center Groningen, Groningen, Netherlands

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• Sharon Geerts,

  Roles Data curation, Formal analysis, Investigation

  Affiliations Center for Engineering in Medicine, Massachusetts General Hospital and Shriners Hospital for Children, Boston, Massachusetts, United States of America, Section of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, University of Groningen, University Medical Center Groningen, Groningen, Netherlands

  ⨯
• Sonal Nagpal,

  Roles Data curation, Formal analysis, Investigation

  Affiliation Center for Engineering in Medicine, Massachusetts General Hospital and Shriners Hospital for Children, Boston, Massachusetts, United States of America

  ⨯
• Ehab O. A. Hafiz,

  Roles Data curation, Formal analysis, Visualization

  Affiliation Electron Microscopy Research Division, Theodor Bilharz Research Institute, Giza, Egypt

  http://orcid.org/0000-0002-1551-4309

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• Fermin M. Fontan,

  Roles Data curation, Investigation, Methodology

  Affiliation Center for Engineering in Medicine, Massachusetts General Hospital and Shriners Hospital for Children, Boston, Massachusetts, United States of America

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• Mohamed M. Aburawi,

  Roles Data curation, Investigation, Methodology

  Affiliation Center for Engineering in Medicine, Massachusetts General Hospital and Shriners Hospital for Children, Boston, Massachusetts, United States of America

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• Paria Mahboub,

  Roles Formal analysis, Investigation, Methodology, Visualization

  Affiliation Center for Engineering in Medicine, Massachusetts General Hospital and Shriners Hospital for Children, Boston, Massachusetts, United States of America

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• James F. Markmann,

  Roles Conceptualization, Investigation, Methodology, Supervision, Validation

  Affiliation Division of Transplantation, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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• Robert J. Porte,

  Roles Conceptualization, Resources, Supervision, Validation

  Affiliation Section of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, University of Groningen, University Medical Center Groningen, Groningen, Netherlands

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• Korkut Uygun,

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Writing – review & editing

  Affiliations Division of Transplantation, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Center for Engineering in Medicine, Massachusetts General Hospital and Shriners Hospital for Children, Boston, Massachusetts, United States of America

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• Martin Yarmush,

  Roles Funding acquisition, Project administration, Resources, Supervision, Validation, Writing – review & editing

  Affiliations Division of Transplantation, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Center for Engineering in Medicine, Massachusetts General Hospital and Shriners Hospital for Children, Boston, Massachusetts, United States of America

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•  [ ... ],
• Heidi Yeh

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – review & editing

  * E-mail: hyeh@partners.org

  Affiliation Division of Transplantation, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

  http://orcid.org/0000-0002-7379-0600

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