In silico analysis and high-risk pathogenic phenotype predictions of non-synonymous single nucleotide polymorphisms in human Crystallin beta A4 gene associated with congenital cataract

• Zhenyu Wang ,

  Contributed equally to this work with: Zhenyu Wang, Chen Huang

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – original draft

  Affiliations Department of Ophthalmology, Peking University Third Hospital, Beijing, China, Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, Beijing, China

  http://orcid.org/0000-0001-6458-3944

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• Chen Huang ,

  Contributed equally to this work with: Zhenyu Wang, Chen Huang

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliations Department of Ophthalmology, Peking University Third Hospital, Beijing, China, Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, Beijing, China, Medical Research Center, Peking University Third Hospital, Beijing, China

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• Huibin Lv,

  Roles Data curation, Investigation, Methodology

  Affiliations Department of Ophthalmology, Peking University Third Hospital, Beijing, China, Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, Beijing, China

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• Mingzhou Zhang,

  Roles Data curation, Methodology

  Affiliations Department of Ophthalmology, Peking University Third Hospital, Beijing, China, Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, Beijing, China

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• Xuemin Li

  Roles Conceptualization, Funding acquisition, Supervision, Validation, Visualization, Writing – review & editing

  * E-mail: lxmlxm66@sina.com

  Affiliations Department of Ophthalmology, Peking University Third Hospital, Beijing, China, Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, Beijing, China

  http://orcid.org/0000-0002-4018-9974

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