The pharmacokinetic parameters and the effect of a single and repeated doses of memantine on gastric myoelectric activity in experimental pigs

• Jan Bures ,

  Contributed equally to this work with: Jan Bures, Jaroslav Kvetina, Ilja Tacheci, Jana Zdarova Karasova

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: bures@lfhk.cuni.cz

  Affiliation 2nd Department of Internal Medicine—Gastroenterology, Charles University, Faculty of Medicine in Hradec Kralove and University Hospital, Hradec Kralove, Czech Republic

  http://orcid.org/0000-0003-0326-117X

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• Jaroslav Kvetina ,

  Contributed equally to this work with: Jan Bures, Jaroslav Kvetina, Ilja Tacheci, Jana Zdarova Karasova

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Supervision, Validation, Writing – review & editing

  Affiliation 2nd Department of Internal Medicine—Gastroenterology, Charles University, Faculty of Medicine in Hradec Kralove and University Hospital, Hradec Kralove, Czech Republic

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• Vera Radochova ,

  Roles Conceptualization, Investigation, Methodology, Project administration, Supervision, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation Animal Laboratory, University of Defence, Faculty of Military Health Sciences, Hradec Kralove, Czech Republic

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• Ilja Tacheci ,

  Contributed equally to this work with: Jan Bures, Jaroslav Kvetina, Ilja Tacheci, Jana Zdarova Karasova

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Writing – review & editing

  Affiliation 2nd Department of Internal Medicine—Gastroenterology, Charles University, Faculty of Medicine in Hradec Kralove and University Hospital, Hradec Kralove, Czech Republic

  http://orcid.org/0000-0003-3583-2651

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• Eva Peterova ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation 2nd Department of Internal Medicine—Gastroenterology, Charles University, Faculty of Medicine in Hradec Kralove and University Hospital, Hradec Kralove, Czech Republic

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• David Herman ,

  Roles Conceptualization, Investigation, Validation, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliations Department of Toxicology and Military Pharmacy, University of Defence, Faculty of Military Health Sciences, Hradec Kralove, Czech Republic, Centre of Biomedical Research, University Hospital, Hradec Kralove, Czech Republic

  http://orcid.org/0000-0003-0784-4524

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• Rafael Dolezal ,

  Roles Conceptualization, Investigation, Methodology, Validation, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation Centre of Biomedical Research, University Hospital, Hradec Kralove, Czech Republic

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• Marcela Kopacova ,

  Roles Conceptualization, Investigation, Methodology, Supervision, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation 2nd Department of Internal Medicine—Gastroenterology, Charles University, Faculty of Medicine in Hradec Kralove and University Hospital, Hradec Kralove, Czech Republic

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• Stanislav Rejchrt ,

  Roles Conceptualization, Investigation, Methodology, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation 2nd Department of Internal Medicine—Gastroenterology, Charles University, Faculty of Medicine in Hradec Kralove and University Hospital, Hradec Kralove, Czech Republic

  http://orcid.org/0000-0001-5166-9503

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• Tomas Douda ,

  Roles Conceptualization, Methodology, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation 2nd Department of Internal Medicine—Gastroenterology, Charles University, Faculty of Medicine in Hradec Kralove and University Hospital, Hradec Kralove, Czech Republic

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• Vit Sestak ,

  Roles Conceptualization, Investigation, Methodology, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation Institute of Clinical Biochemistry and Diagnostics, Charles University, Faculty of Medicine in Hradec Kralove and University Hospital, Hradec Kralove, Czech Republic

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• Ladislav Douda ,

  Roles Conceptualization, Data curation, Investigation, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation 2nd Department of Internal Medicine—Gastroenterology, Charles University, Faculty of Medicine in Hradec Kralove and University Hospital, Hradec Kralove, Czech Republic

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• Jana Zdarova Karasova

  Contributed equally to this work with: Jan Bures, Jaroslav Kvetina, Ilja Tacheci, Jana Zdarova Karasova

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Toxicology and Military Pharmacy, University of Defence, Faculty of Military Health Sciences, Hradec Kralove, Czech Republic, Centre of Biomedical Research, University Hospital, Hradec Kralove, Czech Republic

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