High failure rates of protease inhibitor-based antiretroviral treatment in rural Tanzania – A prospective cohort study

• Rahel E. Bircher ,

  Contributed equally to this work with: Rahel E. Bircher, Alex J. Ntamatungiro

  Roles Formal analysis, Funding acquisition, Investigation, Project administration, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Ifakara Health Institute, Ifakara, Tanzania, Swiss Tropical and Public Health Institute, Basel, Switzerland, University of Basel, Basel, Switzerland, Molecular Virology, Department Biomedicine Petersplatz, University of Basel, Basel, Switzerland

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• Alex J. Ntamatungiro ,

  Contributed equally to this work with: Rahel E. Bircher, Alex J. Ntamatungiro

  Roles Conceptualization, Investigation, Methodology, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Ifakara Health Institute, Ifakara, Tanzania

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• Tracy R. Glass,

  Roles Data curation, Formal analysis, Methodology, Supervision, Visualization, Writing – review & editing

  Affiliations Swiss Tropical and Public Health Institute, Basel, Switzerland, University of Basel, Basel, Switzerland

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• Dorcas Mnzava,

  Roles Supervision, Writing – review & editing

  Affiliation Ifakara Health Institute, Ifakara, Tanzania

  ⨯
• Amina Nyuri,

  Roles Supervision, Writing – review & editing

  Affiliation Ifakara Health Institute, Ifakara, Tanzania

  ⨯
• Herry Mapesi,

  Roles Supervision, Writing – review & editing

  Affiliations Ifakara Health Institute, Ifakara, Tanzania, Swiss Tropical and Public Health Institute, Basel, Switzerland, University of Basel, Basel, Switzerland, St. Francis Referral Hospital, Ifakara, Tanzania

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• Daniel H. Paris,

  Roles Writing – review & editing

  Affiliations Swiss Tropical and Public Health Institute, Basel, Switzerland, University of Basel, Basel, Switzerland

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• Manuel Battegay,

  Roles Writing – review & editing

  Affiliations University of Basel, Basel, Switzerland, Departments of Medicine and Clinical Research, Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Switzerland

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• Thomas Klimkait ,

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation Molecular Virology, Department Biomedicine Petersplatz, University of Basel, Basel, Switzerland

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• Maja Weisser ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: maja.weisser@usb.ch

  ¶‡ These authors also contributed equally to this work.

  Affiliations Ifakara Health Institute, Ifakara, Tanzania, Swiss Tropical and Public Health Institute, Basel, Switzerland, University of Basel, Basel, Switzerland, Departments of Medicine and Clinical Research, Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Switzerland

  http://orcid.org/0000-0002-0134-1929

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• on behalf of the KIULARCO study group