Significant changes in synovial fluid microRNAs after high tibial osteotomy in medial compartmental knee osteoarthritis: Identification of potential prognostic biomarkers

Yoon Hae Kwak; Dae-Kyung Kwak; Nan Young Kim; Yun Joong Kim; Jeong Seop Lim; Je-Hyun Yoo

doi:10.1371/journal.pone.0227596

Loading metrics

Open Access

Peer-reviewed

Research Article

Significant changes in synovial fluid microRNAs after high tibial osteotomy in medial compartmental knee osteoarthritis: Identification of potential prognostic biomarkers

Yoon Hae Kwak ,

Contributed equally to this work with: Yoon Hae Kwak, Dae-Kyung Kwak

Roles Conceptualization, Investigation, Methodology, Project administration, Visualization, Writing – original draft

Affiliation Department of Orthopaedic Surgery, Severance Children’s Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea

http://orcid.org/0000-0002-0596-1228

⨯
Dae-Kyung Kwak ,

Contributed equally to this work with: Yoon Hae Kwak, Dae-Kyung Kwak

Roles Investigation, Validation, Writing – original draft

Affiliation Department of Orthopaedic Surgery, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Republic of Korea
⨯
Nan Young Kim,

Roles Data curation, Software, Validation

Affiliation Hallym Institute of Translational Genomics & Bioinformatics, Hallym University Medical Center, Anyang, Republic of Korea
⨯
Yun Joong Kim,

Roles Supervision

Affiliations Hallym Institute of Translational Genomics & Bioinformatics, Hallym University Medical Center, Anyang, Republic of Korea, Ilsong Institute of Life Science, Hallym University, Anyang, Republic of Korea, Department of Neurology, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Republic of Korea
⨯
Jeong Seop Lim,

Roles Data curation, Project administration

Affiliation Department of Orthopaedic Surgery, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Republic of Korea
⨯
Je-Hyun Yoo

Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Resources, Software, Visualization, Writing – original draft, Writing – review & editing

* E-mail: oships@hallym.ac.kr

Affiliation Department of Orthopaedic Surgery, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Republic of Korea

http://orcid.org/0000-0002-0777-1575

⨯

Significant changes in synovial fluid microRNAs after high tibial osteotomy in medial compartmental knee osteoarthritis: Identification of potential prognostic biomarkers

Yoon Hae Kwak,
Dae-Kyung Kwak,
Nan Young Kim,
Yun Joong Kim,
Jeong Seop Lim,
Je-Hyun Yoo

Published: January 10, 2020
https://doi.org/10.1371/journal.pone.0227596

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

MicroRNAs
Is the Subject Area "MicroRNAs" applicable to this article?

Thanks for your feedback.
Osteoarthritis
Is the Subject Area "Osteoarthritis" applicable to this article?

Thanks for your feedback.
Knees
Is the Subject Area "Knees" applicable to this article?

Thanks for your feedback.
Pain
Is the Subject Area "Pain" applicable to this article?

Thanks for your feedback.
Biomarkers
Is the Subject Area "Biomarkers" applicable to this article?

Thanks for your feedback.
Cartilage
Is the Subject Area "Cartilage" applicable to this article?

Thanks for your feedback.
Polymerase chain reaction
Is the Subject Area "Polymerase chain reaction" applicable to this article?

Thanks for your feedback.
Synovial fluid
Is the Subject Area "Synovial fluid" applicable to this article?

Thanks for your feedback.