Key necroptotic proteins are required for Smac mimetic-mediated sensitization of cholangiocarcinoma cells to TNF-α and chemotherapeutic gemcitabine-induced necroptosis

• Perawatt Akara-amornthum,

  Roles Data curation, Funding acquisition, Investigation, Methodology

  Affiliation Graduate Program in Clinical Biochemistry and Molecular Medicine, Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok, Thailand

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• Thanpisit Lomphithak,

  Roles Data curation, Investigation, Methodology

  Affiliation Graduate Program in Clinical Biochemistry and Molecular Medicine, Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok, Thailand

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• Swati Choksi,

  Roles Resources, Supervision, Writing – review & editing

  Affiliation Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Convent Drive, Bethesda, MD, United States of America

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• Rutaiwan Tohtong,

  Roles Funding acquisition, Resources, Supervision, Writing – review & editing

  Affiliation Department of Biochemistry, Faculty of Science, Mahidol University, Bangkok, Thailand

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• Siriporn Jitkaew

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: Siriporn.ji@chula.ac.th

  Affiliation Age-Related Inflammation and Degeneration Research Unit, Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok, Thailand

  http://orcid.org/0000-0002-7931-2319

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