Pepsin promotes laryngopharyngeal neoplasia by modulating signaling pathways to induce cell proliferation

• Kai Niu ,

  Contributed equally to this work with: Kai Niu, Chunjie Guo

  Roles Conceptualization, Data curation, Methodology, Supervision, Writing – original draft

  Affiliation Department of Otolaryngology Head and Neck Surgery, the First Hospital of Jilin University, Changchun, PR China

  http://orcid.org/0000-0003-2040-6887

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• Chunjie Guo ,

  Contributed equally to this work with: Kai Niu, Chunjie Guo

  Roles Conceptualization, Methodology, Validation

  Affiliation Department of Radiology, the First Hospital of Jilin University, Changchun, PR China

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• Shiyong Teng,

  Roles Data curation, Project administration

  Affiliation Department of Anesthesiology, the First Hospital of Jilin University, Changchun, PR China

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• Dandan Zhou,

  Roles Formal analysis, Methodology

  Affiliation Department of Radiology, the First Hospital of Jilin University, Changchun, PR China

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• Shuyuan Yu,

  Roles Methodology, Validation

  Affiliation Department of Otolaryngology Head and Neck Surgery, the First Hospital of Jilin University, Changchun, PR China

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• Wanzhong Yin,

  Roles Data curation, Funding acquisition, Project administration, Supervision

  Affiliation Department of Otolaryngology Head and Neck Surgery, the First Hospital of Jilin University, Changchun, PR China

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• Ping Wang ,

  Roles Conceptualization, Funding acquisition, Methodology, Supervision

  * E-mail: zhuwei30000@163.com (WZ); wangping99@hotmail.com (PW)

  ¶‡ These authors also contributed equally to this work.

  Affiliation Department of Otolaryngology Head and Neck Surgery, the First Hospital of Jilin University, Changchun, PR China

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• Wei Zhu ,

  Roles Methodology, Supervision, Writing – review & editing

  * E-mail: zhuwei30000@163.com (WZ); wangping99@hotmail.com (PW)

  ¶‡ These authors also contributed equally to this work.

  Affiliation Department of Otolaryngology Head and Neck Surgery, the First Hospital of Jilin University, Changchun, PR China

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• Maoli Duan

  Roles Conceptualization, Writing – review & editing

  Affiliation Department of Clinical Science, Intervention and Technology, Department of Otolaryngology Head and Neck Surgery, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden

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