Aqueous extract from Mangifera indica Linn. (Anacardiaceae) leaves exerts long-term hypoglycemic effect, increases insulin sensitivity and plasma insulin levels on diabetic Wistar rats

• Gustavo Roberto Villas Boas ,

  Contributed equally to this work with: Gustavo Roberto Villas Boas, João Marcos Rodrigues Lemos, Matheus William de Oliveira, Rafael Claudino dos Santos, Marina Meirelles Paes, Priscila Gubert

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: gustavo.villasboas@gmail.com

  Affiliations Research Group on Development of Pharmaceutical Products (P&DProFar), Center for Biological and Health Sciences, Federal University of Western Bahia, Barreiras, Bahia, Brazil, Faculty of Health Sciences, Federal University of Grande Dourados, Dourados, Mato Grosso do Sul, Brazil

  http://orcid.org/0000-0003-1660-6480

  ⨯
• João Marcos Rodrigues Lemos ,

  Contributed equally to this work with: Gustavo Roberto Villas Boas, João Marcos Rodrigues Lemos, Matheus William de Oliveira, Rafael Claudino dos Santos, Marina Meirelles Paes, Priscila Gubert

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Faculty of Health Sciences, University Center of Grande Dourados, Dourados, Mato Grosso do Sul, Brazil

  ⨯
• Matheus William de Oliveira ,

  Contributed equally to this work with: Gustavo Roberto Villas Boas, João Marcos Rodrigues Lemos, Matheus William de Oliveira, Rafael Claudino dos Santos, Marina Meirelles Paes, Priscila Gubert

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Faculty of Health Sciences, University Center of Grande Dourados, Dourados, Mato Grosso do Sul, Brazil

  ⨯
• Rafael Claudino dos Santos ,

  Contributed equally to this work with: Gustavo Roberto Villas Boas, João Marcos Rodrigues Lemos, Matheus William de Oliveira, Rafael Claudino dos Santos, Marina Meirelles Paes, Priscila Gubert

  Roles Data curation, Investigation, Methodology, Resources, Writing – review & editing

  Affiliation Faculty of Health Sciences, Federal University of Grande Dourados, Dourados, Mato Grosso do Sul, Brazil

  ⨯
• Ana Paula Stefanello da Silveira ,

  Roles Conceptualization, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation Faculty of Health Sciences, University Center of Grande Dourados, Dourados, Mato Grosso do Sul, Brazil

  ⨯
• Flávia Barbieri Bacha ,

  Roles Investigation, Methodology, Visualization, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation Faculty of Health Sciences, University Center of Grande Dourados, Dourados, Mato Grosso do Sul, Brazil

  ⨯
• Caren Naomi Aguero Ito ,

  Roles Investigation, Methodology, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation Faculty of Health Sciences, University Center of Grande Dourados, Dourados, Mato Grosso do Sul, Brazil

  ⨯
• Ediane Bortolotte Cornelius ,

  Roles Investigation, Methodology, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation Faculty of Health Sciences, University Center of Grande Dourados, Dourados, Mato Grosso do Sul, Brazil

  ⨯
• Fernanda Brioli Lima ,

  Roles Investigation, Methodology, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation Faculty of Health Sciences, University Center of Grande Dourados, Dourados, Mato Grosso do Sul, Brazil

  ⨯
• Andrea Marisa Sachilarid Rodrigues ,

  Roles Investigation, Methodology, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation Faculty of Health Sciences, University Center of Grande Dourados, Dourados, Mato Grosso do Sul, Brazil

  ⨯
• Nathália Belmal Costa ,

  Roles Investigation, Methodology, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation Faculty of Health Sciences, University Center of Grande Dourados, Dourados, Mato Grosso do Sul, Brazil

  ⨯
• Felipe Francisco Bittencourt ,

  Roles Investigation, Methodology, Resources, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation Faculty of Health Sciences, University Center of Grande Dourados, Dourados, Mato Grosso do Sul, Brazil

  ⨯
• Fernando Freitas de Lima ,

  Roles Conceptualization, Visualization, Writing – original draft, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation Faculty of Health Sciences, Federal University of Grande Dourados, Dourados, Mato Grosso do Sul, Brazil

  ⨯
• Marina Meirelles Paes ,

  Contributed equally to this work with: Gustavo Roberto Villas Boas, João Marcos Rodrigues Lemos, Matheus William de Oliveira, Rafael Claudino dos Santos, Marina Meirelles Paes, Priscila Gubert

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Research Group on Development of Pharmaceutical Products (P&DProFar), Center for Biological and Health Sciences, Federal University of Western Bahia, Barreiras, Bahia, Brazil

  ⨯
• Priscila Gubert ,

  Contributed equally to this work with: Gustavo Roberto Villas Boas, João Marcos Rodrigues Lemos, Matheus William de Oliveira, Rafael Claudino dos Santos, Marina Meirelles Paes, Priscila Gubert

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Research Group on Development of Pharmaceutical Products (P&DProFar), Center for Biological and Health Sciences, Federal University of Western Bahia, Barreiras, Bahia, Brazil, Department of Biochemistry, Laboratory of Imunopathology Keizo Asami, Federal University of Pernambuco, Recife, Brazil

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•  [ ... ],
• Silvia Aparecida Oesterreich

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation Faculty of Health Sciences, Federal University of Grande Dourados, Dourados, Mato Grosso do Sul, Brazil

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