Modeling succinate dehydrogenase loss disorders in C. elegans through effects on hypoxia-inducible factor

Megan M. Braun; Tamara Damjanac; Yuxia Zhang; Chuan Chen; Jinghua Hu; L. James Maher III

doi:10.1371/journal.pone.0227033

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Peer-reviewed

Research Article

Modeling succinate dehydrogenase loss disorders in C. elegans through effects on hypoxia-inducible factor

Megan M. Braun,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

Current address: University of Wisconsin–Madison Neuroscience Training Program, Madison, WI, United States of America

Affiliation Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Science, Rochester, MN, United States of America
⨯
Tamara Damjanac,

Roles Data curation, Investigation, Methodology, Validation

Current address: University of Minnesota Medical School–Twin Cities, Minneapolis, MN, United States of America

Affiliation Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Science, Rochester, MN, United States of America
⨯
Yuxia Zhang,

Roles Methodology, Supervision

Current address: MD Anderson Cancer Center, the University of Texas, Dallas, TX, United States of America

Affiliation Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Science, Rochester, MN, United States of America
⨯
Chuan Chen,

Roles Methodology, Supervision

Affiliation Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Science, Rochester, MN, United States of America
⨯
Jinghua Hu,

Roles Conceptualization, Funding acquisition, Supervision, Validation, Visualization, Writing – review & editing

Affiliation Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Science, Rochester, MN, United States of America
⨯
L. James Maher III

Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

* E-mail: maher@mayo.edu

Affiliation Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine and Science, Rochester, MN, United States of America

http://orcid.org/0000-0002-5043-6422

⨯

Modeling succinate dehydrogenase loss disorders in C. elegans through effects on hypoxia-inducible factor

Megan M. Braun,
Tamara Damjanac,
Yuxia Zhang,
Chuan Chen,
Jinghua Hu,
L. James Maher III

Published: December 30, 2019
https://doi.org/10.1371/journal.pone.0227033

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