Allergic inflammation is initiated by IL-33–dependent crosstalk between mast cells and basophils

Chia-Lin Hsu; Krishan D. Chhiba; Rebecca Krier-Burris; Shweta Hosakoppal; Sergejs Berdnikovs; Mendy L. Miller; Paul J. Bryce

doi:10.1371/journal.pone.0226701

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Open Access

Peer-reviewed

Research Article

Allergic inflammation is initiated by IL-33–dependent crosstalk between mast cells and basophils

Chia-Lin Hsu ,

Contributed equally to this work with: Chia-Lin Hsu, Krishan D. Chhiba

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – review & editing

Affiliation Division of Allergy-Immunology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States of America
⨯
Krishan D. Chhiba ,

Contributed equally to this work with: Chia-Lin Hsu, Krishan D. Chhiba

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

Affiliation Division of Allergy-Immunology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States of America
⨯
Rebecca Krier-Burris,

Roles Formal analysis, Investigation, Methodology, Validation

Affiliation Division of Allergy-Immunology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States of America
⨯
Shweta Hosakoppal,

Roles Formal analysis, Investigation, Methodology

Affiliation Division of Allergy-Immunology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States of America
⨯
Sergejs Berdnikovs,

Roles Data curation, Formal analysis, Visualization

Affiliation Division of Allergy-Immunology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States of America
⨯
Mendy L. Miller,

Roles Conceptualization, Project administration, Writing – original draft, Writing – review & editing

Affiliation Division of Allergy-Immunology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States of America
⨯
Paul J. Bryce

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Validation, Writing – original draft, Writing – review & editing

* E-mail: paul.bryce@sanofi.com

Current address: Immunology & Inflammation Therapeutic Area, Sanofi US, Cambridge, MA, United States of America

Affiliation Division of Allergy-Immunology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States of America

http://orcid.org/0000-0001-6455-3155

⨯

Allergic inflammation is initiated by IL-33–dependent crosstalk between mast cells and basophils

Chia-Lin Hsu,
Krishan D. Chhiba,
Rebecca Krier-Burris,
Shweta Hosakoppal,
Sergejs Berdnikovs,
Mendy L. Miller,
Paul J. Bryce

Published: January 15, 2020
https://doi.org/10.1371/journal.pone.0226701

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Basophils
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Mast cells
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Inflammation
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Ears
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Inflammatory diseases
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Flow cytometry
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Allergies
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