Entropy of human leukocyte antigen and killer-cell immunoglobulin-like receptor systems in immune-mediated disorders: A pilot study on multiple sclerosis

• Maurizio Melis ,

  Contributed equally to this work with: Maurizio Melis, Roberto Littera

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: roby.litter@gmail.com (RL); maurizio.melis@gmail.com (MM); luchinochessa@unica.it (LC)

  Affiliation Medical Genetics, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy

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• Roberto Littera ,

  Contributed equally to this work with: Maurizio Melis, Roberto Littera

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: roby.litter@gmail.com (RL); maurizio.melis@gmail.com (MM); luchinochessa@unica.it (LC)

  Affiliation Complex Structure of Medical Genetics, R. Binaghi Hospital, ASSL Cagliari, ATS Sardegna, Italy

  http://orcid.org/0000-0003-3143-3792

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• Eleonora Cocco,

  Roles Data curation, Resources, Writing – review & editing

  Affiliation Multiple Sclerosis Center, R. Binaghi Hospital, University of Cagliari/ATS Sardegna, Cagliari, Italy

  ⨯
• Jessica Frau,

  Roles Data curation, Resources

  Affiliation Multiple Sclerosis Center, R. Binaghi Hospital, University of Cagliari/ATS Sardegna, Cagliari, Italy

  ⨯
• Sara Lai,

  Roles Data curation, Formal analysis

  Affiliation Complex Structure of Medical Genetics, R. Binaghi Hospital, ASSL Cagliari, ATS Sardegna, Italy

  ⨯
• Elena Congeddu,

  Roles Formal analysis

  Affiliation Medical Genetics, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy

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• Paola Ragatzu,

  Roles Formal analysis

  Affiliation Medical Genetics, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy

  ⨯
• Maria Serra,

  Roles Formal analysis

  Affiliation Complex Structure of Medical Genetics, R. Binaghi Hospital, ASSL Cagliari, ATS Sardegna, Italy

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• Valentina Loi,

  Roles Formal analysis

  Affiliation Complex Structure of Medical Genetics, R. Binaghi Hospital, ASSL Cagliari, ATS Sardegna, Italy

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• Roberta Maddi,

  Roles Formal analysis

  Affiliation Complex Structure of Medical Genetics, R. Binaghi Hospital, ASSL Cagliari, ATS Sardegna, Italy

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• Roberta Pitzalis,

  Roles Data curation, Resources

  Affiliation Multiple Sclerosis Center, R. Binaghi Hospital, University of Cagliari/ATS Sardegna, Cagliari, Italy

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• Sandro Orrù,

  Roles Data curation, Investigation, Resources

  Affiliation Medical Genetics, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy

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• Luchino Chessa ,

  Roles Investigation, Resources, Writing – review & editing

  * E-mail: roby.litter@gmail.com (RL); maurizio.melis@gmail.com (MM); luchinochessa@unica.it (LC)

  Affiliation Center for the Study of Liver Diseases, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy

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• Andrea Perra ,

  Roles Conceptualization, Formal analysis, Investigation, Project administration, Resources, Supervision, Validation, Visualization, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation Unit of Oncology and Molecular Pathology, Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy

  ⨯
• Carlo Carcassi

  Roles Conceptualization, Formal analysis, Investigation, Project administration, Resources, Supervision, Validation, Visualization, Writing – review & editing

  ¶‡ These authors also contributed equally to this work.

  Affiliation Medical Genetics, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy

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