Modulation of T helper 1 and T helper 2 immune balance in a murine stress model during Chlamydia muridarum genital infection

Tesfaye Belay; Elisha Martin; Gezelle Brown; Raenel Crenshaw; Julia Street; Ashleigh Freeman; Shane Musick; Tyler J. Kinder

doi:10.1371/journal.pone.0226539

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Open Access

Peer-reviewed

Research Article

Modulation of T helper 1 and T helper 2 immune balance in a murine stress model during Chlamydia muridarum genital infection

Tesfaye Belay ,

Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

* E-mail: tbelay@bluefieldstate.edu

Affiliation Bluefield State College, Bluefield, WV, United States of America

http://orcid.org/0000-0001-9055-3749

⨯
Elisha Martin,

Roles Data curation, Methodology

Affiliation Bluefield State College, Bluefield, WV, United States of America
⨯
Gezelle Brown,

Roles Conceptualization, Data curation, Investigation, Methodology

Affiliation Bluefield State College, Bluefield, WV, United States of America
⨯
Raenel Crenshaw,

Roles Conceptualization, Data curation, Methodology, Writing – original draft

Affiliation Bluefield State College, Bluefield, WV, United States of America
⨯
Julia Street,

Roles Conceptualization, Data curation, Formal analysis, Investigation

Current address: Appalachian Regional Healthcare, Hinton, WV, United States of America

Affiliation Bluefield State College, Bluefield, WV, United States of America
⨯
Ashleigh Freeman,

Roles Conceptualization, Data curation, Investigation, Methodology

Current address: Princeton High School, Princeton, WV, United States of America

Affiliation Bluefield State College, Bluefield, WV, United States of America
⨯
Shane Musick,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology

Current address: Medical School of Marshall University, Huntington, WV, United States of America

Affiliation Bluefield State College, Bluefield, WV, United States of America
⨯
Tyler J. Kinder

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

Current address: Dept of Molecular and Cellular Biochemistry, University of KY, Lexington, KY, United States of America

Affiliation Bluefield State College, Bluefield, WV, United States of America
⨯

Modulation of T helper 1 and T helper 2 immune balance in a murine stress model during Chlamydia muridarum genital infection

Tesfaye Belay,
Elisha Martin,
Gezelle Brown,
Raenel Crenshaw,
Julia Street,
Ashleigh Freeman,
Shane Musick,
Tyler J. Kinder

Published: May 15, 2020
https://doi.org/10.1371/journal.pone.0226539

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T cells
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Chlamydia infection
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Cytokines
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Gene expression
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Mouse models
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T helper cells
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Cell differentiation
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Thermal stresses
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