The metronomic combination of paclitaxel with cholinergic agonists inhibits triple negative breast tumor progression. Participation of M₂ receptor subtype

• Alejandro J. Español ,

  Contributed equally to this work with: Alejandro J. Español, Agustina Salem

  Roles Data curation, Formal analysis, Investigation

  * E-mail: aespan_1999@yahoo.com (AJE); adamaria.tata@uniroma1.it (AMT)

  Affiliations Center of Pharmacological and Botanical Studies (CEFYBO), CONICET, Buenos Aires, Argentine, Department of Pharmacology, School of Medicine, University of Buenos Aires, Buenos Aires, Argentine, Department of Biology and Biotechnologies Charles Darwin, Sapienza University of Rome, Rome, Italy

  http://orcid.org/0000-0001-8222-4259

  ⨯
• Agustina Salem ,

  Contributed equally to this work with: Alejandro J. Español, Agustina Salem

  Roles Data curation, Formal analysis, Investigation

  Affiliations Center of Pharmacological and Botanical Studies (CEFYBO), CONICET, Buenos Aires, Argentine, Department of Pharmacology, School of Medicine, University of Buenos Aires, Buenos Aires, Argentine

  ⨯
• María Di Bari,

  Roles Investigation, Methodology

  Affiliation Department of Biology and Biotechnologies Charles Darwin, Sapienza University of Rome, Rome, Italy

  ⨯
• Ilaria Cristofaro,

  Roles Investigation, Methodology

  Affiliation Department of Biology and Biotechnologies Charles Darwin, Sapienza University of Rome, Rome, Italy

  ⨯
• Yamila Sanchez,

  Roles Investigation, Methodology

  Affiliations Center of Pharmacological and Botanical Studies (CEFYBO), CONICET, Buenos Aires, Argentine, Department of Pharmacology, School of Medicine, University of Buenos Aires, Buenos Aires, Argentine

  ⨯
• Ada M. Tata ,

  Roles Conceptualization, Funding acquisition, Project administration

  * E-mail: aespan_1999@yahoo.com (AJE); adamaria.tata@uniroma1.it (AMT)

  Affiliations Department of Biology and Biotechnologies Charles Darwin, Sapienza University of Rome, Rome, Italy, Center of Neurobiology Daniel Bovet, Sapienza University of Rome, Rome, Italy

  ⨯
• María E. Sales

  Roles Conceptualization, Funding acquisition, Project administration

  Affiliations Center of Pharmacological and Botanical Studies (CEFYBO), CONICET, Buenos Aires, Argentine, Department of Pharmacology, School of Medicine, University of Buenos Aires, Buenos Aires, Argentine

  ⨯