TRPC3 determines osmosensitive [Ca2+]i signaling in the collecting duct and contributes to urinary concentration

Viktor N. Tomilin; Mykola Mamenko; Oleg Zaika; Guohui Ren; Sean P. Marrelli; Lutz Birnbaumer; Oleh Pochynyuk

doi:10.1371/journal.pone.0226381

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Open Access

Peer-reviewed

Research Article

TRPC3 determines osmosensitive [Ca²⁺]_i signaling in the collecting duct and contributes to urinary concentration

Viktor N. Tomilin,

Roles Formal analysis, Investigation, Writing – review & editing

Affiliation Department of Integrative Biology and Pharmacology, the University of Texas Health Science Center at Houston, Houston, Texas, United States of America
⨯
Mykola Mamenko,

Roles Conceptualization, Formal analysis, Investigation, Writing – review & editing

Affiliation Department of Physiology, Medical College of Georgia, Augusta University, Augusta, Georgia, United States of America
⨯
Oleg Zaika,

Roles Formal analysis, Investigation, Writing – review & editing

Affiliation Department of Integrative Biology and Pharmacology, the University of Texas Health Science Center at Houston, Houston, Texas, United States of America
⨯
Guohui Ren,

Roles Formal analysis, Investigation

Affiliation Department of Integrative Biology and Pharmacology, the University of Texas Health Science Center at Houston, Houston, Texas, United States of America
⨯
Sean P. Marrelli,

Roles Conceptualization, Writing – review & editing

Affiliation Department of Neurology, the University of Texas Health Science Center at Houston, Houston, Texas, United States of America
⨯
Lutz Birnbaumer,

Roles Conceptualization, Writing – review & editing

Affiliations Neurobiology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, United States of America, Institute of Biomedical Research (BIOMED), School of Medical Sciences, Catholic University of Argentina, Buenos Aires, Argentina
⨯
Oleh Pochynyuk

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

* E-mail: Oleh.M.Pochynyuk@uth.tmc.edu

Affiliation Department of Integrative Biology and Pharmacology, the University of Texas Health Science Center at Houston, Houston, Texas, United States of America

http://orcid.org/0000-0002-5397-6897

⨯

TRPC3 determines osmosensitive [Ca²⁺]_i signaling in the collecting duct and contributes to urinary concentration

Viktor N. Tomilin,
Mykola Mamenko,
Oleg Zaika,
Guohui Ren,
Sean P. Marrelli,
Lutz Birnbaumer,
Oleh Pochynyuk

Published: December 18, 2019
https://doi.org/10.1371/journal.pone.0226381

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