Stable depletion of RUNX1-ETO in Kasumi-1 cells induces expression and enhanced proteolytic activity of Cathepsin G and Neutrophil Elastase

• Caroline Schoenherr,

  Roles Conceptualization, Data curation, Investigation, Methodology, Writing – original draft

  Affiliation Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany

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• Katharina Wohlan,

  Roles Data curation

  Affiliation Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany

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• Iris Dallmann,

  Roles Data curation, Methodology

  Affiliation Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany

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• Andreas Pich,

  Roles Conceptualization, Methodology, Validation

  Affiliation Department of Toxicology, Research Core Unit Proteomics, Hannover Medical School, Hannover, Germany

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• Jan Hegermann,

  Roles Data curation, Methodology

  Affiliation Department of Functional and Applied Anatomy, Research Core Unit Electron Microscopy, Hannover Medical School, Hannover, Germany

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• Arnold Ganser,

  Roles Writing – review & editing

  Affiliation Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany

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• Denise Hilfiker-Kleiner,

  Roles Conceptualization

  Affiliation Department of Cardiology and Angiology, Hannover Medical School, Hannover, Germany

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• Olaf Heidenreich,

  Roles Conceptualization, Writing – review & editing

  Affiliations Wolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle, United Kingdom, Princess Maxima Center for Pediatric Oncology, Utrecht, Netherlands

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• Michaela Scherr ,

  Contributed equally to this work with: Michaela Scherr, Matthias Eder

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

  * E-mail: Scherr.Michaela@mh-hannover.de (MS); Eder.Matthias@mh-hannover.de (ME)

  Affiliation Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany

  http://orcid.org/0000-0001-6409-215X

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• Matthias Eder

  Contributed equally to this work with: Michaela Scherr, Matthias Eder

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

  * E-mail: Scherr.Michaela@mh-hannover.de (MS); Eder.Matthias@mh-hannover.de (ME)

  Affiliation Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany

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