Erastin, a ferroptosis-inducing agent, sensitized cancer cells to X-ray irradiation via glutathione starvation in vitro and in vivo

• Yuki Shibata,

  Roles Conceptualization, Investigation, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Biomedical Imaging, Graduate School of Biomedical Science and Engineering, Hokkaido University, Sapporo, Hokkaido, Japan

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• Hironobu Yasui ,

  Roles Conceptualization, Investigation, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: yassan@vetmed.hokudai.ac.jp

  Affiliations Department of Biomedical Imaging, Graduate School of Biomedical Science and Engineering, Hokkaido University, Sapporo, Hokkaido, Japan, Central Institute of Isotope Science, Hokkaido University, Sapporo, Hokkaido, Japan, Laboratory of Radiation Biology, Department of Applied Veterinary Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Hokkaido, Japan

  http://orcid.org/0000-0002-6757-1110

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• Kei Higashikawa,

  Roles Investigation, Validation, Writing – review & editing

  Affiliations Department of Biomedical Imaging, Graduate School of Biomedical Science and Engineering, Hokkaido University, Sapporo, Hokkaido, Japan, Central Institute of Isotope Science, Hokkaido University, Sapporo, Hokkaido, Japan

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• Naoki Miyamoto,

  Roles Investigation, Writing – review & editing

  Affiliation Faculty of Engineering, Hokkaido University, Sapporo, Hokkaido, Japan

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• Yuji Kuge

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliations Department of Biomedical Imaging, Graduate School of Biomedical Science and Engineering, Hokkaido University, Sapporo, Hokkaido, Japan, Central Institute of Isotope Science, Hokkaido University, Sapporo, Hokkaido, Japan

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