Combination treatment of berberine and solid lipid curcumin particles increased cell death and inhibited PI3K/Akt/mTOR pathway of human cultured glioblastoma cells more effectively than did individual treatments

• Panchanan Maiti ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: maiti1p@cmich.edu(PM); dunba1g@cmich.edu(GLD)

  Affiliations Field Neurosciences Institute Laboratory for Restorative Neurology, Central Michigan University, Mt. Pleasant, MI, United States of America, Program in Neuroscience, Central Michigan University, Mt. Pleasant, MI, United States of America, Department of Psychology, Central Michigan University, Mt. Pleasant, MI, United States of America, Field Neurosciences Institute, Ascension of St. Mary’s Hospital, Saginaw, MI, United States of America, Department of Biology, Saginaw Valley State University, Saginaw, MI, United States of America

  http://orcid.org/0000-0003-3213-8015

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• Alexandra Plemmons,

  Roles Data curation, Writing – review & editing

  Affiliation Field Neurosciences Institute Laboratory for Restorative Neurology, Central Michigan University, Mt. Pleasant, MI, United States of America

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• Gary L. Dunbar

  Roles Funding acquisition, Visualization, Writing – review & editing

  * E-mail: maiti1p@cmich.edu(PM); dunba1g@cmich.edu(GLD)

  Affiliations Field Neurosciences Institute Laboratory for Restorative Neurology, Central Michigan University, Mt. Pleasant, MI, United States of America, Program in Neuroscience, Central Michigan University, Mt. Pleasant, MI, United States of America, Department of Psychology, Central Michigan University, Mt. Pleasant, MI, United States of America, Field Neurosciences Institute, Ascension of St. Mary’s Hospital, Saginaw, MI, United States of America

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