Characterization of the relationship between neutron production and thermal load on a target material in an accelerator-based boron neutron capture therapy system employing a solid-state Li target

• Satoshi Nakamura,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Medical Physics, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan, Division of Research and Development for Boron Neutron Capture Therapy, National Cancer Center Exploratory Oncology Research & Clinical Trial Center, Chuo-ku, Tokyo, Japan

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• Hiroshi Igaki ,

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Writing – review & editing

  * E-mail: hirigaki@ncc.go.jp

  Affiliations Division of Research and Development for Boron Neutron Capture Therapy, National Cancer Center Exploratory Oncology Research & Clinical Trial Center, Chuo-ku, Tokyo, Japan, Department of Radiation Oncology, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan

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• Masashi Ito,

  Roles Data curation, Investigation, Methodology

  Affiliation Department of Radiology, National Center for Global Health and Medicine, Shinjuku-ku, Tokyo, Japan

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• Hiroyuki Okamoto,

  Roles Conceptualization, Data curation, Investigation, Methodology, Validation

  Affiliations Department of Medical Physics, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan, Division of Research and Development for Boron Neutron Capture Therapy, National Cancer Center Exploratory Oncology Research & Clinical Trial Center, Chuo-ku, Tokyo, Japan

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• Shie Nishioka,

  Roles Conceptualization, Data curation, Validation

  Affiliations Department of Medical Physics, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan, Division of Research and Development for Boron Neutron Capture Therapy, National Cancer Center Exploratory Oncology Research & Clinical Trial Center, Chuo-ku, Tokyo, Japan

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• Kotaro Iijima,

  Roles Conceptualization, Data curation, Validation

  Affiliation Department of Medical Physics, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan

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• Hiroki Nakayama,

  Roles Conceptualization, Data curation, Validation

  Affiliations Department of Medical Physics, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan, Department of Radiological Science, Graduate School of Human Health Sciences, Arakawa-ku, Tokyo, Japan

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• Mihiro Takemori,

  Roles Conceptualization, Data curation, Validation

  Affiliations Department of Medical Physics, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan, Department of Radiological Science, Graduate School of Human Health Sciences, Arakawa-ku, Tokyo, Japan

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• Shoji Imamichi,

  Roles Conceptualization, Data curation

  Affiliations Division of Research and Development for Boron Neutron Capture Therapy, National Cancer Center Exploratory Oncology Research & Clinical Trial Center, Chuo-ku, Tokyo, Japan, Lab of Collaborative Research, Division of Cellular Signaling, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan

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• Tairo Kashihara,

  Roles Conceptualization, Data curation

  Affiliation Department of Radiation Oncology, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan

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• Kana Takahashi,

  Roles Resources

  Affiliation Department of Radiation Oncology, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan

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• Koji Inaba,

  Roles Resources

  Affiliation Department of Radiation Oncology, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan

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• Kae Okuma,

  Roles Resources

  Affiliation Department of Radiation Oncology, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan

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• Naoya Murakami,

  Roles Resources

  Affiliation Department of Radiation Oncology, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan

  http://orcid.org/0000-0003-0660-9987

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• Yoshihisa Abe,

  Roles Conceptualization, Resources, Validation

  Affiliations Division of Research and Development for Boron Neutron Capture Therapy, National Cancer Center Exploratory Oncology Research & Clinical Trial Center, Chuo-ku, Tokyo, Japan, Department of Radiological Technology, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan

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• Yuko Nakayama,

  Roles Resources

  Affiliation Department of Radiation Oncology, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan

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• Mitsuko Masutani,

  Roles Resources, Writing – review & editing

  Affiliations Division of Research and Development for Boron Neutron Capture Therapy, National Cancer Center Exploratory Oncology Research & Clinical Trial Center, Chuo-ku, Tokyo, Japan, Lab of Collaborative Research, Division of Cellular Signaling, National Cancer Center Research Institute, Chuo-ku, Tokyo, Japan, Center for Bioinformatics and Molecular Medicine, Department of Frontier Life Sciences, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto, Nagasaki, Japan

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• Teiji Nishio,

  Roles Resources, Writing – review & editing

  Affiliation Department of Medical Physics, Graduate School of Medicine, Tokyo Women’s Medical University, Shinjuku-ku, Tokyo, Japan

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•  [ ... ],
• Jun Itami

  Roles Funding acquisition, Project administration, Writing – review & editing

  Affiliations Department of Medical Physics, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan, Division of Research and Development for Boron Neutron Capture Therapy, National Cancer Center Exploratory Oncology Research & Clinical Trial Center, Chuo-ku, Tokyo, Japan, Department of Radiation Oncology, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan

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