Robust blind spectral unmixing for fluorescence microscopy using unsupervised learning

• Tristan D. McRae,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Multiphoton Research Core Facility, Shared Resource Laboratories, University of Rochester Medical Center, Rochester, NY, United States of America, Department of Neuroscience, University of Rochester Medical Center, Rochester, NY, United States of America

  ⨯
• David Oleksyn,

  Roles Investigation, Methodology, Validation, Writing – review & editing

  Affiliation Center for Vaccine Biology and Immunology and Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY, United States of America

  ⨯
• Jim Miller,

  Roles Funding acquisition, Investigation, Methodology, Resources, Supervision, Writing – review & editing

  Affiliation Center for Vaccine Biology and Immunology and Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY, United States of America

  ⨯
• Yu-Rong Gao

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: yurong_gao@urmc.rochester.edu

  Affiliations Multiphoton Research Core Facility, Shared Resource Laboratories, University of Rochester Medical Center, Rochester, NY, United States of America, Department of Neuroscience, University of Rochester Medical Center, Rochester, NY, United States of America

  http://orcid.org/0000-0001-8363-6757

  ⨯