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Open Access

Peer-reviewed

Research Article

Metformin strongly affects transcriptome of peripheral blood cells in healthy individuals

Monta Briviba,

Roles Investigation, Writing – original draft

Affiliation Latvian Biomedical Research and Study Centre, Riga, Latvia
⨯
Ivars Silamikelis,

Roles Data curation, Formal analysis

Affiliation Latvian Biomedical Research and Study Centre, Riga, Latvia
⨯
Ineta Kalnina,

Roles Funding acquisition

Affiliation Latvian Biomedical Research and Study Centre, Riga, Latvia
⨯
Laura Ansone,

Roles Investigation

Affiliation Latvian Biomedical Research and Study Centre, Riga, Latvia
⨯
Vita Rovite,

Roles Resources

Affiliation Latvian Biomedical Research and Study Centre, Riga, Latvia
⨯
Ilze Elbere,

Roles Resources

Affiliation Latvian Biomedical Research and Study Centre, Riga, Latvia
⨯
Ilze Radovica-Spalvina,

Roles Investigation

Affiliation Latvian Biomedical Research and Study Centre, Riga, Latvia
⨯
Davids Fridmanis,

Roles Resources

Affiliation Latvian Biomedical Research and Study Centre, Riga, Latvia
⨯
Jekaterina Aladyeva,

Roles Visualization

Affiliation Latvian Biomedical Research and Study Centre, Riga, Latvia
⨯
Ilze Konrade,

Roles Resources

Affiliation Riga Stradins University, Riga, Latvia
⨯
Valdis Pirags,

Roles Resources, Supervision

Affiliation Latvian Biomedical Research and Study Centre, Riga, Latvia
⨯
Janis Klovins

Roles Conceptualization, Project administration, Supervision

* E-mail: Klovins@biomed.lu.lv

Affiliation Latvian Biomedical Research and Study Centre, Riga, Latvia

http://orcid.org/0000-0001-8362-5505

⨯

Metformin strongly affects transcriptome of peripheral blood cells in healthy individuals

Monta Briviba,
Ivars Silamikelis,
Ineta Kalnina,
Laura Ansone,
Vita Rovite,
Ilze Elbere,
Ilze Radovica-Spalvina,
Davids Fridmanis,
Jekaterina Aladyeva,
Ilze Konrade

x

Published: November 8, 2019
https://doi.org/10.1371/journal.pone.0224835

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CD coreceptors
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Gene expression
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Gastrointestinal tract
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Transcriptome analysis
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RNA sequencing
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Cancer treatment
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Gene ontologies
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Immune response
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